Bouza C, López T, Palma M, Amate J M
Agency for Health Technology Assessment, Ministry of Health and Consumer Affairs, Madrid, Spain.
Osteoporos Int. 2007 May;18(5):649-57. doi: 10.1007/s00198-006-0292-x. Epub 2007 Jan 13.
This population-based study reveals clinical and epidemiologic characteristics of hospitalised osteoporosis-related vertebral fractures and indicates an association with a substantial hospital burden in Spain. These data provide a basis for assessing the impact of these fractures on the Spanish health-care system and to estimate future care requirements.
Vertebral fractures (VF) are recognised as the most frequent complication of osteoporosis. Our objective was to determine the clinico-epidemiological characteristics and health-care burden of hospitalised VF in Spain.
From the 2002 National Hospital Discharge Register, records for all osteoporosis-related VF in the Spanish population aged >or=30 years and over were retrieved. Diagnostic categories included the ICD-9-CM codes 805 and 733.xx. Population data were drawn from the National Statistics Institute.
In total, 7,100 records were eligible for analysis. According to Deyo-adapted Charlson index, 62% of cases had no associated comorbidity. VF were the cause of hospitalisation in 52% of cases. Overall in-hospital mortality was 3.5%. Men had higher adjusted mortality than women. Mean hospital stay was 11.4+/-0.2 days. Identified cases amounted to a hospitalisation rate of 2.76 cases per 10,000 population aged >or=30 years. Direct inpatient hospital costs exceeded 41 million euros and accounted for 0.078% of Spanish expenditure on hospitalisations and specialised care in 2002.
The national discharge database reveals epidemiological features of hospitalised osteoporosis-attributable VF and indicates an association with a substantial hospital burden in Spain. Our data provide a basis for assessing the impact of these fractures on the Spanish health-care system and to estimate future care requirements.
这项基于人群的研究揭示了住院骨质疏松相关椎体骨折的临床和流行病学特征,并表明其与西班牙大量的医院负担存在关联。这些数据为评估这些骨折对西班牙医疗保健系统的影响以及估计未来护理需求提供了依据。
椎体骨折(VF)被认为是骨质疏松最常见的并发症。我们的目标是确定西班牙住院VF的临床流行病学特征和医疗保健负担。
从2002年国家医院出院登记册中检索西班牙30岁及以上人群中所有与骨质疏松相关的VF记录。诊断类别包括ICD-9-CM编码805和733.xx。人口数据来自国家统计局。
总共7100条记录符合分析条件。根据改良的Deyo查尔森指数,62%的病例无相关合并症。52%的病例中VF是住院原因。总体住院死亡率为3.5%。男性调整后的死亡率高于女性。平均住院时间为11.4±0.2天。已识别病例的住院率为每10000名30岁及以上人群中有2.76例。2002年住院患者直接医院费用超过4100万欧元,占西班牙住院和专科护理支出的0.078%。
国家出院数据库揭示了住院骨质疏松所致VF的流行病学特征,并表明其与西班牙大量的医院负担存在关联。我们的数据为评估这些骨折对西班牙医疗保健系统的影响以及估计未来护理需求提供了依据。