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患有创伤性网胃炎的牛的凝血谱、生化和血液学参数变化

Alterations in coagulation profiles and biochemical and haematological parameters in cattle with traumatic reticuloperitonitis.

作者信息

Gokce H I, Gokce G, Cihan M

机构信息

Department of Internal Medicine, University of Kafkas, Kars, Turkey.

出版信息

Vet Res Commun. 2007 Jul;31(5):529-37. doi: 10.1007/s11259-007-3527-1. Epub 2007 Jan 15.

Abstract

This study was designed to investigate alterations in coagulation, and in biochemical and haematological parameters in cattle with traumatic reticuloperitonitis (TRP). In the study, 28 dairy cattle with TRP and 10 clinically healthy cattle (control) of different ages and breeds were used. Cattle with TRP had prolonged prothrombin time (PT), thrombin time (TT) and activated partial thromboplastin time (APTT). Erythrocytopenia, thrombocytopenia and hyperfibrinogenaemia were detected in animals with TRP. Furthermore, the serum concentrations of total protein, globulin and total bilirubin, and the activities of alkaline phosphatase (ALP) and aspartate aminotransferase (AST) were also high in cattle with TRP compared to those of the control group. The serum concentrations of calcium were significantly low in the TRP group. The results of this study, therefore, indicate that TRP causes significant coagulation abnormalities and biochemical and haematological alterations in dairy cattle.

摘要

本研究旨在调查患有创伤性网胃炎(TRP)的奶牛的凝血功能以及生化和血液学参数的变化。在该研究中,使用了28头患有TRP的奶牛和10头不同年龄和品种的临床健康奶牛(对照组)。患有TRP的奶牛凝血酶原时间(PT)、凝血酶时间(TT)和活化部分凝血活酶时间(APTT)延长。在患有TRP的动物中检测到红细胞减少、血小板减少和纤维蛋白原血症。此外,与对照组相比,患有TRP的奶牛血清总蛋白、球蛋白和总胆红素浓度以及碱性磷酸酶(ALP)和天冬氨酸转氨酶(AST)活性也较高。TRP组血清钙浓度显著降低。因此,本研究结果表明,TRP会导致奶牛出现明显的凝血异常以及生化和血液学改变。

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