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关于慢性疾病患者流感疫苗安全性的误解。

Misperceptions regarding influenza vaccine safety for individuals with chronic medical illness.

作者信息

Kempe Allison, Daley Matthew F, Crane Lori A, Barrow Jennifer, Chandramouli Vijayalaxmi, Beaty Brenda L, Allred Norma J, Berman Stephen

机构信息

Departments of Pediatrics, University of Colorado School of Medicine, Denver, CO, USA.

出版信息

Prev Med. 2007 Jul;45(1):80-2. doi: 10.1016/j.ypmed.2006.12.001. Epub 2007 Jan 17.

Abstract

BACKGROUND

Influenza immunization is recommended for adults >or=50 years, healthy children 6-59 months and individuals with a chronic medical condition.

OBJECTIVES

To compare respondents' perceptions of safety of immunization for children and adults both with and without chronic medical conditions.

METHODS

We surveyed parents of 828 randomly selected healthy children aged 6-21 months of age from 5 pediatric practices in Denver, Colorado between August and October of 2003.

RESULTS

The survey response rate was 57% (n=472). Although 65% of parents thought influenza immunization was safe for healthy 1 year olds, only 40% considered it safe for 1 year olds with a chronic condition. Similarly, 86% judged it safe in healthy 70 year olds versus 50% in 70 year olds with a chronic condition.

CONCLUSIONS

Educational efforts to encourage influenza immunization in individuals with chronic illnesses should highlight the message that a chronic medical condition is an indication for immunization and does not confer additional risk of complications from vaccination. Further research is needed to confirm and better understand the observed perception of vulnerability to adverse events of vaccines in those with chronic illness.

摘要

背景

建议50岁及以上成年人、6至59个月的健康儿童以及患有慢性疾病的个体接种流感疫苗。

目的

比较受访者对患有和未患有慢性疾病的儿童及成年人接种疫苗安全性的看法。

方法

2003年8月至10月期间,我们对科罗拉多州丹佛市5家儿科诊所随机抽取的828名6至21个月大健康儿童的家长进行了调查。

结果

调查回复率为57%(n = 472)。虽然65%的家长认为流感疫苗对健康的1岁儿童是安全的,但只有40%的家长认为对患有慢性疾病的1岁儿童是安全的。同样,86%的家长认为对健康的70岁老人是安全的,而患有慢性疾病的70岁老人中这一比例为50%。

结论

鼓励慢性病患者接种流感疫苗的教育工作应强调,慢性病是接种疫苗的指征,不会增加接种疫苗出现并发症的额外风险。需要进一步研究来证实并更好地理解观察到的慢性病患者对疫苗不良事件易感性的看法。

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