Department of Biology, B-022, University of California at San Diego, La Jolla, CA 92093.
Genetics. 1982 May;101(1):81-9. doi: 10.1093/genetics/101.1.81.
The effects of eight recombination-defective meiotic mutants on crossing over within the X heterochromatin were examined. Since none permit substantial frequencies of exchange within heterochromatin although six lessen or abolish constraints on the location of exchanges within euchromatin, the systems that prohibit exchange within heterochromatin and that govern where exchanges will occur in euchromatin are under separate genetic control.-A minor component of the effects of mei-218 is the production of nonhomologous exchanges; of mei-9 is the recovery of deleted chromatids; and of mei-41 is the recovery of deleted chromatids and/or a low frequency of heterochromatic exchanges.
研究了 8 种重组缺陷的减数分裂突变体对 X 染色体异染色质内交叉的影响。尽管有 6 种突变体减少或消除了异染色质内交换位置的限制,但它们都不能允许在异染色质内发生大量的交换,因此,禁止异染色质内交换和控制异染色质内交换位置的系统受到独立的遗传控制。mei-218 的一个次要作用是产生非同源交换;mei-9 的作用是恢复缺失的染色单体;mei-41 的作用是恢复缺失的染色单体和/或异染色质内交换的低频发生。