Vargas Kaaren G, Packham Brett, Lowman David
Pediatric Dentistry, College of Dentistry, The University of Iowa, Iowa City, USA.
Pediatr Dent. 2006 Nov-Dec;28(6):511-7.
The purpose of this study was to compare the effectiveness of 5% sodium hypochlorite (NaOCl) to that of ferric sulfate (FeSO4) as a pulpotomy medicament in decayed primary molars.
Healthy subjects between 4 and 9 years with at least 2 primary molars needing pulpotomy consented to receive either NaOCl or FeSO4 and restoration with IRM base/stainless steel crown in a prospective, randomized design. Clinical and radiographic signs/symptoms were recorded at 0, 6, and 12 months.
Twenty-three subjects were recruited. Six-month results are based on the first 32 teeth in the NaOCl group and 28 teeth in the FeSO4 group. Twelve-month results are based on 13 teeth in the FeSO4 group and 14 in the NaOCl group. Results show 100% restoration retention in both groups and no signs/symptoms of pain at 6 and 12 months. At 6 months, 100% clinical success was found with both FeSO4 and NaOCl. Radiographic success for FeSO4 was 68%, with internal resorption being the most common finding. The NaOCl group showed 91% radiographic success, P = .050. At 12 months, FeSO4 had 85% clinical success and 62% radiographic success. NaOCl had 100% clinical success and 79% radiographic success.
Preliminary evidence shows that NaOCl can be used successfully as a pulpotomy medicament.
本研究旨在比较5%次氯酸钠(NaOCl)与硫酸铁(FeSO4)作为乳牙龋坏牙髓切断术药物的有效性。
4至9岁、至少有2颗需要进行牙髓切断术的健康乳牙的受试者,同意接受NaOCl或FeSO4治疗,并采用IRM基底/不锈钢冠进行修复,采用前瞻性随机设计。在0、6和12个月时记录临床和影像学体征/症状。
招募了23名受试者。6个月的结果基于NaOCl组的前32颗牙齿和FeSO4组的28颗牙齿。12个月的结果基于FeSO4组的13颗牙齿和NaOCl组的14颗牙齿。结果显示两组修复体保留率均为100%,在6个月和12个月时均无疼痛体征/症状。在6个月时,FeSO4和NaOCl的临床成功率均为100%。FeSO4的影像学成功率为68%,最常见的表现是内部吸收。NaOCl组的影像学成功率为91%,P = 0.050。在12个月时,FeSO4的临床成功率为85%,影像学成功率为62%。NaOCl的临床成功率为100%,影像学成功率为79%。
初步证据表明,NaOCl可成功用作牙髓切断术药物。