An efficient diastereoselective route to differentially protected anti-4-amino-1-alken-3-ols.

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作者信息

Lombardo Marco, Mosconi Elisa, Pasi Filippo, Petrini Marino, Trombini Claudio

机构信息

Dipartimento di Chimica G. Ciamician, Università di Bologna, via Selmi 2, I-40126 Bologna, Italy.

出版信息

J Org Chem. 2007 Mar 2;72(5):1834-7. doi: 10.1021/jo062265n. Epub 2007 Jan 24.

DOI:10.1021/jo062265n

PMID:17249733

Abstract

Zinc-promoted hydroxyallylation of alpha-amidoalkyl arylsulfones 4 using 3-bromo-propenyl methyl carbonate 5 proceeds smoothly in DMF at room temperature to afford high yields of differentially protected anti-1,2-amino alcohols 6.

摘要

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