从粘毛旋覆花中分离鉴定一种新型抗真菌倍半萜内酯
Isolation and Identification of a New Antifungal Sesquiterpene Lactone from Inula viscosa.
作者信息
Maoz M, Kashman Y, Neeman I
机构信息
Department of Food Engineering and Biotechnology, Technion, Haifa, Israel.
出版信息
Planta Med. 1999 Apr;65(3):281-2. doi: 10.1055/s-2006-960780.
PMID:17260308
Abstract
A new sesquiterpene - tayunin - has been isolated and purified from powdered leaves of INULA VISCOSA (L.) Ait. The chemical structure was determined by 1D and 2D NMR analysis, and IR and MS. Tayunin inhibits the growth of MICROSPORUM CANIS at a concentration of 10 microg/ml and TRICHOPHYTON RUBRUM at 50 microg/ml(MIC).
摘要
从粘毛旋覆花（Inula viscosa (L.) Ait.）的粉末状叶子中分离并纯化出一种新的倍半萜——塔云宁。通过一维和二维核磁共振分析、红外光谱和质谱确定了其化学结构。塔云宁在浓度为10微克/毫升时可抑制犬小孢子菌（Microsporum canis）的生长，在浓度为50微克/毫升（最小抑菌浓度）时可抑制红色毛癣菌（Trichophyton rubrum）的生长。
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