Benharash Peyman, Lee Jason T, Abilez Oscar J, Crabtree Tami, Bloch Daniel A, Zarins Christopher K
Department of Surgery, Division of Vascular Surgery, Stanford University School of Medicine, Stanford, CA 94305-5431, USA.
J Vasc Surg. 2007 Feb;45(2):250-7. doi: 10.1016/j.jvs.2006.09.061.
To evaluate the role of iliac fixation in preventing migration of suprarenal and infrarenal aortic endografts.
Quantitative image analysis was performed in 92 patients with infrarenal aortic aneurysms (76 men and 16 women) treated with suprarenal (n = 36) or infrarenal (n = 56) aortic endografts from 2000 to 2004. The longitudinal centerline distance from the superior mesenteric artery to the top of the stent graft was measured on preoperative, postimplantation, and 1-year three-dimensional computed tomographic scans, with movement more than 5 mm considered to be significant. Aortic diameters were measured perpendicular to the centerline axis. Proximal and distal fixation lengths were defined as the lengths of stent-graft apposition to the aortic neck and the common iliac arteries, respectively.
There were no significant differences in age, comorbidities, or preoperative aneurysm size (suprarenal, 6.0 cm; infrarenal, 5.7 cm) between the suprarenal and infrarenal groups. However, the suprarenal group had less favorable aortic necks with a shorter length (13 vs 25 mm; P < .0001), a larger diameter (27 vs 24 mm; P < .0001), and greater angulation (19 degrees vs 11 degrees ; P = .007) compared with the infrarenal group. The proximal aortic fixation length was greater in the suprarenal than in the infrarenal group (22 vs 16 mm; P < .0001), with the top of the device closer to the superior mesenteric artery (8 vs 21 mm; P < .0001) as a result of the 15-mm uncovered suprarenal stent. There was no difference in iliac fixation length between the suprarenal and infrarenal groups (26 vs 25 mm; P = .8). Longitudinal centerline stent graft movement at 1 year was similar in the suprarenal and infrarenal groups (4.3 +/- 4.4 mm vs 4.8 +/- 4.3 mm; P = .6). Patients with longitudinal centerline movement of more than 5 mm at 1 year or clinical evidence of migration at any time during the follow-up period comprised the respective migrator groups. Suprarenal migrators had a shorter iliac fixation length (17 vs 29 mm; P = .006) and a similar aortic fixation length (23 vs 22 mm; P > .999) compared with suprarenal nonmigrators. Infrarenal migrators had a shorter iliac fixation length (18 vs 30 mm; P < .0001) and a similar aortic fixation length (14 vs 17 mm; P = .1) compared with infrarenal nonmigrators. Nonmigrators had closer device proximity to the hypogastric arteries in both the suprarenal (7 vs 17 mm; P = .009) and infrarenal (8 vs 24 mm; P < .0001) groups. No migration occurred in either group in patients with good iliac fixation. Multivariate logistic regression analysis revealed that iliac fixation, as evidenced by iliac fixation length (P = .004) and the device to hypogastric artery distance (P = .002), was a significant independent predictor of migration, whereas suprarenal or infrarenal treatment was not a significant predictor of migration. During a clinical follow-up period of 45 +/- 22 months (range, 12-70 months), there have been no aneurysm ruptures, abdominal aortic aneurysm-related deaths, or surgical conversions in either group.
Distal iliac fixation is important in preventing migration of both suprarenal and infrarenal aortic endografts that have longitudinal columnar support. Secure iliac fixation minimizes the risk of migration despite suboptimal proximal aortic neck anatomy. Extension of both iliac limbs to cover the entire common iliac artery to the iliac bifurcation seems to prevent endograft migration.
评估髂动脉固定在预防肾上型和肾下型主动脉腔内移植物移位中的作用。
对2000年至2004年接受肾上型(n = 36)或肾下型(n = 56)主动脉腔内移植物治疗的92例肾下型主动脉瘤患者(76例男性和16例女性)进行定量图像分析。在术前、植入后及1年时的三维计算机断层扫描上测量从肠系膜上动脉到支架移植物顶端的纵向中心线距离,移动超过5 mm被认为有意义。垂直于中心线轴测量主动脉直径。近端和远端固定长度分别定义为支架移植物与主动脉颈部和髂总动脉贴合的长度。
肾上型和肾下型组在年龄、合并症或术前动脉瘤大小(肾上型为6.0 cm;肾下型为5.7 cm)方面无显著差异。然而,与肾下型组相比,肾上型组的主动脉颈部条件较差,长度较短(13 vs 25 mm;P <.0001),直径较大(27 vs 24 mm;P <.0001),成角更大(19度 vs 11度;P =.007)。肾上型组的近端主动脉固定长度大于肾下型组(22 vs 16 mm;P <.0001),由于有15 mm无覆盖的肾上型支架,移植物顶端更靠近肠系膜上动脉(8 vs 21 mm;P <.0001)。肾上型和肾下型组的髂动脉固定长度无差异(26 vs 25 mm;P =.8)。肾上型和肾下型组在1年时纵向中心线支架移植物移动情况相似(4.3±4.4 mm vs 4.8±4.3 mm;P =.6)。1年时纵向中心线移动超过5 mm或随访期间任何时间有移位临床证据的患者分别构成各自的移位组。与肾上型未移位患者相比,肾上型移位患者的髂动脉固定长度较短(17 vs 29 mm;P =.006),主动脉固定长度相似(23 vs 22 mm;P >.999)。与肾下型未移位患者相比,肾下型移位患者的髂动脉固定长度较短(18 vs 30 mm;P <.