Szücs A, Stefano G B, Hughes T K, Rózsa K S
Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany.
Acta Biochim Biophys Hung. 1991;26(1-4):139-43.
The modulatory effects of interleukin-1 (IL-1), an immunotransmitter, and FMRFamide, a molluscan neuropeptide, were studied on identified neurons of Helix pomatia L. (Mollusca, Gastropoda) by using the method of two microelectrode voltage clamp. IL-1 and FMRFamide uniformly decreased the voltage-activated inward current (ICa), while the voltage-dependent outward potassium current (Inet K) increased. IL-1 and FMRFamide were shown to use the same cellular targets as used by the low molecular weight neurotransmitters.