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Various signal molecules modulate voltage-activated ion currents on snail neurons.

作者信息

Szücs A, Stefano G B, Hughes T K, Rózsa K S

机构信息

Balaton Limnological Research Institute, Hungarian Academy of Sciences, Tihany.

出版信息

Acta Biochim Biophys Hung. 1991;26(1-4):139-43.

PMID:1726948
Abstract

The modulatory effects of interleukin-1 (IL-1), an immunotransmitter, and FMRFamide, a molluscan neuropeptide, were studied on identified neurons of Helix pomatia L. (Mollusca, Gastropoda) by using the method of two microelectrode voltage clamp. IL-1 and FMRFamide uniformly decreased the voltage-activated inward current (ICa), while the voltage-dependent outward potassium current (Inet K) increased. IL-1 and FMRFamide were shown to use the same cellular targets as used by the low molecular weight neurotransmitters.

摘要

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