Lee Keith L, Stoller Marshall L
Department of Urology, University of California San Francisco, San Francisco, California 94143-0738, USA.
Curr Opin Urol. 2007 Mar;17(2):120-4. doi: 10.1097/MOU.0b013e328010ca76.
As urologists will continue to rely on percutaneous nephrolithotomy, a clear understanding of its associated bleeding risks and management is mandatory.
Despite advances in lithotripsy technology, bleeding continues to be a cause of patient morbidity in percutaneous nephrolithotomy. Although most patients can be managed conservatively, a subset of patients will require endovascular embolization for vascular control. Investigators have identified risk factors and described management options. The use of different dilators and tract size continues to be examined. Additionally, novel applications of proclotting agents as well as direct renal and tract electrocauterization immediately postpercutaneous nephrolithotomy have been reported to decrease transfusions. Finally, initial access obtained by the urologist is associated with less bleeding and higher stone-free rates.
Optimal renal access is the most critical factor influencing surgical success and minimizing overall blood loss. Although real-time ultrasonography may add to the safety of the initial access, surgeon experience is the key factor. As such, the urologist must be actively involved in tract placement. Clinically significant bleeding can be treated conservatively in a majority of cases with tamponade nephrostomy tubes with or without transfusions. Arterial hemorrhage, pseudoaneurysms, and arterial-venous fistulas, however, require prompt intervention with angiographic embolization.
由于泌尿外科医生将继续依赖经皮肾镜取石术,因此必须清楚了解其相关的出血风险及处理方法。
尽管碎石技术有所进步,但出血仍是经皮肾镜取石术患者发病的一个原因。虽然大多数患者可通过保守治疗,但有一部分患者需要进行血管内栓塞以控制出血。研究人员已确定了风险因素并描述了处理方案。不同扩张器的使用和通道大小仍在研究中。此外,据报道,在经皮肾镜取石术后立即使用促凝血剂以及直接对肾脏和通道进行电灼可减少输血。最后,泌尿外科医生建立的初始通道与较少的出血和较高的结石清除率相关。
最佳的肾脏通道是影响手术成功和减少总体失血量的最关键因素。虽然实时超声检查可能会增加初始通道建立的安全性,但外科医生的经验是关键因素。因此,泌尿外科医生必须积极参与通道的放置。在大多数情况下,通过填塞肾造瘘管,无论是否输血,都可对具有临床意义的出血进行保守治疗。然而,动脉出血、假性动脉瘤和动静脉瘘需要通过血管造影栓塞进行及时干预。