菌毛糖基化基因pglA的相位可变等位基因与从播散性淋球菌感染患者分离出的淋病奈瑟菌菌株没有强烈关联。
The phase-variable allele of the pilus glycosylation gene pglA is not strongly associated with strains of Neisseria gonorrhoeae isolated from patients with disseminated gonococcal infection.
作者信息
Power P M, Ku S C, Rutter K, Warren M J, Limnios E A, Tapsall J W, Jennings M P
机构信息
School of Molecular and Microbial Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
出版信息
Infect Immun. 2007 Jun;75(6):3202-4. doi: 10.1128/IAI.01501-06. Epub 2007 Feb 12.
Abstract
The Neisseria gonorrhoeae pglA gene has two alleles, one of which is phase variable. A previous study reported that all disseminated gonococcal infection (DGI) isolates contained the phase-variable allele and proposed a causal link. In the present study of 81 strains no absolute correlation between DGI and the phase-variable pglA allele was observed.
摘要
淋病奈瑟菌pglA基因有两个等位基因，其中一个是相位可变的。先前的一项研究报告称，所有播散性淋球菌感染（DGI）分离株都含有相位可变等位基因，并提出了因果关系。在本研究的81株菌株中，未观察到DGI与相位可变pglA等位基因之间存在绝对相关性。
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