Funaki Kaoru, Fukunishi Hidenobu, Funaki Tsuyoshi, Sawada Katsuhiro, Kaji Yasushi, Maruo Takeshi
Department of Gynecology, Shinsuma Hospital, Hyogo, Japan.
Am J Obstet Gynecol. 2007 Feb;196(2):184.e1-6. doi: 10.1016/j.ajog.2006.08.030.
This study was undertaken to clarify the relationship between the signal intensity of T2-weighted magnetic resonance images and the therapeutic effect of magnetic resonance-guided focused ultrasound surgery (MRgFUS) on uterine fibroids.
Ninety-five fibroids in 63 patients were classified into 3 types based on the signal intensity of T2-weighted magnetic resonance images as follows: type 1, low intensity; type 2, intermediate intensity; type 3, high intensity. The treated area ratio of MRgFUS and the volume reduction ratio 6 months after treatment were used as the indices of therapeutic effect.
The treated area ratio of type 3 fibroids was the lowest among the 3 types (P < .01). The volume reduction ratio correlated with the treated area ratio (r = 0.64; P < .01).
The efficacy of MRgFUS correlates with the signal intensity of T2-weighted magnetic resonance images. Type 1 and type 2 fibroids are suitable candidates for MRgFUS, whereas type 3 fibroids are not.
本研究旨在阐明T2加权磁共振图像的信号强度与磁共振引导聚焦超声手术（MRgFUS）治疗子宫肌瘤的疗效之间的关系。
根据T2加权磁共振图像的信号强度，将63例患者的95个肌瘤分为3种类型，如下：1型，低信号强度；2型，中等信号强度；3型，高信号强度。将MRgFUS的治疗面积比和治疗后6个月的体积缩小率作为疗效指标。
3型肌瘤的治疗面积比在3种类型中最低（P < 0.01）。体积缩小率与治疗面积比相关（r = 0.64；P < 0.01）。
MRgFUS的疗效与T2加权磁共振图像的信号强度相关。1型和2型肌瘤是MRgFUS的合适治疗对象，而3型肌瘤则不适合。
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