Galassi Fernando, Giambene Barbara, Corvi Andrea, Falaschi Giacomo
Eye Clinic, University of Florence, via Santa Marta, 24 - 50139 Florence, Italy.
Br J Ophthalmol. 2007 Jul;91(7):878-81. doi: 10.1136/bjo.2007.114397. Epub 2007 Feb 21.
Ocular surface temperature (OST) could berelated to retrobulbar haemodynamics in patients with glaucoma.
To compare OST measurements in patients with glaucoma and healthy controls, and to investigate the correlation between OST, intraocular pressure (IOP) and retrobulbar haemodynamics in patients with glaucoma.
32 patients with primary open-angle glaucoma (POAG) and 40 controls were included in the study. The parameters considered both in patients with POAG and in controls were IOP and OST values measured by infrared ocular thermography. Colour Doppler imaging was used to determine haemodynamic parameters in ophthalmic artery (OA), central retinal artery (CRA) and short posterior ciliary arteries (SPCAs) in patients with POAG.
OST values were significantly lower in patients with POAG than in controls (p<0.001). OST was negatively related with resistivity index of OA (p<0.001), CRA (p = 0.001) and SPCAs (p<0.001), and positively related with end-diastolic velocity of OA (p = 0.02) and SPCAs (p = 0.05).
This study suggested that OST could be a marker of impaired retrobulbar haemodynamics in patients with glaucoma.
青光眼患者的眼表温度(OST)可能与球后血流动力学有关。
比较青光眼患者和健康对照者的OST测量值,并研究青光眼患者的OST、眼压(IOP)和球后血流动力学之间的相关性。
本研究纳入了32例原发性开角型青光眼(POAG)患者和40例对照者。POAG患者和对照者均测量的参数为通过红外眼热成像法测得的IOP和OST值。采用彩色多普勒成像测定POAG患者眼动脉(OA)、视网膜中央动脉(CRA)和睫状后短动脉(SPCA)的血流动力学参数。
POAG患者的OST值显著低于对照者(p<0.001)。OST与OA(p<0.001)、CRA(p = 0.001)和SPCA(p<0.001)的阻力指数呈负相关,与OA(p = 0.02)和SPCA(p = 0.05)的舒张末期速度呈正相关。
本研究提示,OST可能是青光眼患者球后血流动力学受损的一个标志物。