来自拟矮鸢尾根茎的抗氧化黄酮类化合物和异黄酮类化合物。

Antioxidant flavonoids and isoflavonoids from rhizomes of Iris pseudopumila.

作者信息

Rigano Daniela, Formisano Carmen, Grassia Armando, Grassia Gianluca, Perrone Angela, Piacente Sonia, Vuotto Maria Luisa, Senatore Felice

机构信息

Department of Chemistry of Natural Products, University of Naples Federico II, Italy.

出版信息

Planta Med. 2007 Jan;73(1):93-6. doi: 10.1055/s-2006-957071.

DOI:10.1055/s-2006-957071

PMID:17315314

Abstract

Chromatographic separation of a methanolic extract from Iris pseudopumila rhizomes led to the isolation of two new natural compounds, irilone 4'-O-[beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside] and isoscutellarein 6-C-beta-D-glucopyranoside, along with 9 isoflavonoids and 4 flavonoids. Their structures were determined on the basis of spectroscopic evidence. Isolated compounds were evaluated for their antioxidant activity using the luminol-dependent chemiluminescence assay, with quercetin as a positive control. Irilone 4'-O-beta-D-glucopyranoside and kaempferol 3-O-[alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside] showed significant antioxidant activity.

摘要

对拟矮鸢尾根茎的甲醇提取物进行色谱分离，得到了两种新的天然化合物，鸢尾酮4'-O-[β-D-吡喃葡萄糖基-(1→6)-β-D-吡喃葡萄糖苷]和异黄芩素6-C-β-D-吡喃葡萄糖苷，以及9种异黄酮和4种黄酮。根据光谱证据确定了它们的结构。以槲皮素作为阳性对照，使用鲁米诺依赖性化学发光分析法对分离得到的化合物进行抗氧化活性评估。鸢尾酮4'-O-β-D-吡喃葡萄糖苷和山奈酚3-O-[α-L-鼠李糖基-(1→6)-β-D-吡喃葡萄糖苷]表现出显著的抗氧化活性。