兽医人员中甲氧西林耐药金黄色葡萄球菌定植情况
Methicillin-resistant Staphylococcus aureus colonization in veterinary personnel.
作者信息
Hanselman Beth A, Kruth Steve A, Rousseau Joyce, Low Donald E, Willey Barbara M, McGeer Allison, Weese J Scott
机构信息
Ontario Veterinary College, University of Guelph, Guelph, Ontario, Canada.
出版信息
Emerg Infect Dis. 2006 Dec;12(12):1933-8. doi: 10.3201/eid1212.060231.
Methicillin-resistant Staphylococcus aureus (MRSA) was isolated from nares of 27/417 (6.5%) attendees at an international veterinary conference: 23/345 (7.0%) veterinarians, 4/34 (12.0%) technicians, and 0/38 others. Colonization was more common for large-animal (15/96, 15.6%) than small-animal personnel (12/271, 4.4%) or those with no animal patient contact (0/50) (p<0.001). Large-animal practice was the only variable significantly associated with colonization (odds ratio 2.9; 95% confidence interval 1.2-6.6). Pulsed-field gel electrophoresis identified 2 predominant clones with similar distribution among veterinarians as previously reported for horses and companion animals. Canadian epidemic MRSA-2 (CMRSA) was isolated from 11 small-animal and 2 large-animal personnel from the United States (n = 12) and Germany (n = 1). In contrast, CMRSA-5 was isolated exclusively from large-animal personnel (p<0.001) in the United States (n = 10), United Kingdom (n = 2), and Denmark (n = 1). MRSA colonization may be an occupational risk for veterinary professionals.
在一次国际兽医会议上，从417名参会者中的27人（6.5%）的鼻腔中分离出耐甲氧西林金黄色葡萄球菌（MRSA）：23名兽医中的345人（7.0%）、4名技术人员中的34人（12.0%）以及38名其他人员中的0人。与小动物接触的人员（12/271，4.4%）或无动物患者接触的人员（0/50）相比，大型动物接触人员（15/96，15.6%）的定植更为常见（p<0.001）。大型动物诊疗工作是与定植显著相关的唯一变量（比值比2.9；95%置信区间1.2 - 6.6）。脉冲场凝胶电泳鉴定出2个主要克隆，其在兽医中的分布与先前报道的马匹和伴侣动物相似。从美国（n = 12）和德国（n = 1）的11名小动物接触人员和2名大型动物接触人员中分离出加拿大流行的MRSA - 2（CMRSA）。相比之下，CMRSA - 5仅从美国（n = 10）、英国（n = 2）和丹麦（n = 1）的大型动物接触人员中分离出（p<0.001）。MRSA定植可能是兽医专业人员的职业风险。
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