McMahon Colin J, Oslizlok Paul, Walsh Kevin P
Department of Paediatric Cardiology, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
Catheter Cardiovasc Interv. 2007 Apr 1;69(5):735-8. doi: 10.1002/ccd.21091.
Traditionally, the implantation of stents in young children with small blood vessels has been avoided as the presence of a metallic or fixed stent structure limits the ability to further dilate the stent with vessel growth. Pulmonary atresia with ventricular septal defect and hypoplastic pulmonary arteries represents one such cohort where the placement of fixed nondegradable stents has been difficult. We report a 2-month-old girl with pulmonary atresia, VSD, and multiple aorto-pulmonary collaterals with severely hypoplastic pulmonary arteries who underwent placement of a biodegradable magnesium stent within a stenotic aorto-pulmonary collateral. Although there was an initial significant increase in vessel diameter, significant restenosis occurred 4 months after stent placement. This to our knowledge represents the first case of the use of biodegradable stents in a child with severely hypoplastic pulmonary arteries. Although further refinements in stent technology are required, this development will hopefully usher in a new era of potential intervention in children previously deemed unsuitable for stent placement.
传统上,由于金属或固定支架结构的存在会限制随着血管生长进一步扩张支架的能力,因此一直避免在血管细小的幼儿中植入支架。室间隔缺损合并肺动脉闭锁及肺动脉发育不全就是这样一组病例,在这类病例中放置固定的不可降解支架一直很困难。我们报告了一名2个月大的女孩,患有肺动脉闭锁、室间隔缺损和多发主肺动脉侧支,肺动脉严重发育不全,她在狭窄的主肺动脉侧支内植入了可生物降解的镁支架。虽然最初血管直径有显著增加,但在支架置入4个月后出现了明显的再狭窄。据我们所知,这是首例在肺动脉严重发育不全的儿童中使用可生物降解支架的病例。尽管支架技术还需要进一步改进,但这一进展有望开创一个对以前被认为不适合放置支架的儿童进行潜在干预的新时代。