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继发于浆细胞瘤的寰椎病理性骨折。

Pathological fracture of the atlas secondary to plasmacytoma.

作者信息

Kotil Kadir

机构信息

Department of Neurosurgery, Haseki Educational and Research Hospital, Istanbul, Turkey.

出版信息

J Clin Neurosci. 2007 May;14(5):492-4. doi: 10.1016/j.jocn.2006.01.030. Epub 2007 Mar 7.

Abstract

Plasmacytoma of the atlas with pathological fracture has not been previously reported. A 72-year-old man was admitted to our clinic with a 5-month history of occipital headache. Neurologic examination revealed mild occipital neuralgia, difficulty with movements of the cranium, hyperactive deep tendon reflexes, but no Babinski sign. Magnetic resonance imaging (MRI) of the cervical spine showed a 1x2 cm well-circumscribed extradural mass, with lytic destruction and fracture of the lateral mass of C1. Preoperatively dynamic cervical radiographs showed no instability. Using a transcondylar approach, the tumor was removed, and posterolateral fixation and fusion (using iliac autograft) was performed. Biopsy was reported as plasmacytoma. The patient was pain-free with bony fusion 3 years after surgery. This paper presents a pathologic fracture of C1. Although the primary treatment of plasmacytoma is non-surgical, the need for tissue diagnosis in relevant areas may dictate an open biopsy procedure. Such cases may require a decompression and reconstruction procedure.

摘要

既往未见关于寰椎浆细胞瘤伴病理性骨折的报道。一名72岁男性因枕部头痛5个月入住我院。神经系统检查发现轻度枕神经痛、颅骨活动困难、腱反射亢进,但未引出巴宾斯基征。颈椎磁共振成像(MRI)显示一个1×2 cm边界清晰的硬膜外肿块,C1侧块有溶骨性破坏和骨折。术前颈椎动态X线片显示无不稳定。采用经髁入路切除肿瘤,并进行后外侧固定和融合(使用自体髂骨移植)。活检报告为浆细胞瘤。术后3年患者骨融合,疼痛消失。本文介绍了C1病理性骨折的情况。虽然浆细胞瘤的主要治疗方法是非手术治疗,但相关区域组织诊断的必要性可能决定采取开放活检手术。此类病例可能需要进行减压和重建手术。

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