核共聚物：基于寡核苷酸的两亲性二嵌段共聚物。
Nucleo-copolymers: oligonucleotide-based amphiphilic diblock copolymers.
作者信息
Teixeira Francisco, Rigler Per, Vebert-Nardin Corinne
机构信息
Departement Chemie, Universität Basel, Klingelbergstrasse 80, CH-4056 Basel, Switzerland.
出版信息
Chem Commun (Camb). 2007 Mar 12(11):1130-2. doi: 10.1039/b617109e. Epub 2007 Feb 6.
DOI:10.1039/b617109e
PMID:17347715
Abstract
For the first time, poly(butadiene) has been covalently linked to an oligonucleotide sequence and the resulting nucleo-copolymer exhibits amphiphilic properties in dilute aqueous solution, self-assembling into nanometer-sized vesicular structures.
摘要
聚丁二烯首次与寡核苷酸序列共价连接，所得的核共聚物在稀水溶液中表现出两亲性，自组装成纳米尺寸的囊泡结构。
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