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阴茎头浸润性鳞状细胞癌的重建手术

Reconstructive surgery for invasive squamous carcinoma of the glans penis.

作者信息

Smith Yuko, Hadway Paul, Biedrzycki Olaf, Perry Matthew J A, Corbishley Catherine, Watkin Nicholas A

机构信息

Department of Urology, St George's Hospital, London, United Kingdom.

出版信息

Eur Urol. 2007 Oct;52(4):1179-85. doi: 10.1016/j.eururo.2007.02.038. Epub 2007 Feb 20.

Abstract

OBJECTIVES

We present medium-term outcome data for patients with invasive penile cancer treated with glansectomy and reconstruction with a split-thickness skin graft.

METHODS

A series of consecutive patients referred with penile malignancies over a 6-yr period were analyzed prospectively. A dedicated histopathologist reviewed all the specimens. After clinical staging, patients with tumours confined to the glans were offered glansectomy.

RESULTS

A total of 72 patients (32% of patients, 31% of procedures) underwent glansectomy for penile carcinoma. Of these, 65 patients were new diagnoses and seven were recurrences after radiotherapy. The mean follow-up period was 27 mo (range: 4-68 mo). There have been three late local recurrences (4%).

CONCLUSION

Glansectomy appears to be an oncologically safe and effective procedure for patients with glans-confined squamous cell tumours. It preserves maximum phallic length and results in a very satisfactory cosmetic penile appearance after reconstruction.

摘要

目的

我们展示了采用龟头切除术及中厚皮片移植重建术治疗浸润性阴茎癌患者的中期结果数据。

方法

对连续6年转诊来的一系列阴茎恶性肿瘤患者进行前瞻性分析。由一名专业病理学家复查所有标本。临床分期后,为肿瘤局限于龟头的患者施行龟头切除术。

结果

共有72例患者(占患者总数的32%,占手术例数的31%)因阴茎癌接受了龟头切除术。其中,65例为新诊断病例,7例为放疗后复发病例。平均随访期为27个月(范围:4 - 68个月)。有3例晚期局部复发(4%)。

结论

对于肿瘤局限于龟头的鳞状细胞肿瘤患者,龟头切除术似乎是一种肿瘤学上安全有效的手术。它能保留最大阴茎长度,重建后阴茎外观非常令人满意。

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