Larsen S H, Wagner G, Heitmann B L
Research Unit for Dietary Studies, Institute of Preventive Medicine, Copenhagen University Hospital, Centre for Health and Society, Copenhagen, Denmark.
Int J Obes (Lond). 2007 Aug;31(8):1189-98. doi: 10.1038/sj.ijo.0803604. Epub 2007 Mar 20.
To review the literature on the relationship between obesity and sexual function.
A search in the medical literature from 1966 and onwards was carried out through Medline and Embase for publications on obesity, in combination with Medical Subject Heading words related to sexual function and dysfunction.
Four prospective and seven cross-sectional studies were found describing association between obesity and erectile dysfunction (ED). One cross-sectional study was found describing obesity and female sexual dysfunction (FSD). The prospective studies on ED all demonstrated a direct association and so did five of the seven cross-sectional studies. The single FSD study did not find any relationship. Eight intervention studies on weight loss and sexual difficulties were identified. All included few individuals and results were mixed even if most indicated an increase of sexual activity among both men and women after weight loss intervention.
Support for the assumption that obesity is associated with ED was found in both prospective and cross-sectional studies. FSD was not adequately described in the literature and prospective studies are needed here. Results from weight loss intervention studies are less conclusive, but also point toward improvement in sexual dysfunction with reduced weight.
回顾关于肥胖与性功能之间关系的文献。
通过Medline和Embase对1966年及以后的医学文献进行检索，查找关于肥胖的出版物，并结合与性功能和功能障碍相关的医学主题词。
发现四项前瞻性研究和七项横断面研究描述了肥胖与勃起功能障碍（ED）之间的关联。发现一项横断面研究描述了肥胖与女性性功能障碍（FSD）之间的关系。关于ED的前瞻性研究均表明存在直接关联，七项横断面研究中的五项也是如此。唯一的FSD研究未发现任何关系。确定了八项关于减肥与性困难的干预研究。所有研究纳入的个体均较少，结果参差不齐，尽管大多数研究表明减肥干预后男性和女性的性活动均有所增加。
前瞻性研究和横断面研究均支持肥胖与ED相关的假设。文献中对FSD的描述不够充分，在此方面需要进行前瞻性研究。减肥干预研究的结果不太具有决定性，但也表明体重减轻后性功能障碍会有所改善。
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