Wagner H, Neidhardt U, Tittel G
Institut für Pharmazeutische Arzneimittellehre der Universität München, Bundesrepublik Deutschland.
Planta Med. 1981 Mar;41(3):232-9. doi: 10.1055/s-2007-971708.
A new TLC- and HPLC-method for the detection and estimation of the main alkaloids from Symphytum roots, Symphytine, Echimidine, Lycopsamine, and Acetyllycopsamine in their genuine N-oxide form is described. The method provides characteristic finger-prints for the constituents of the Symphytum drugs of different origin and varying harvest seasons.