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近50年华西地区涎腺肿瘤病例临床分析

Clinical analysis of salivary gland tumor cases in West China in past 50 years.

作者信息

Li Long-Jiang, Li Yi, Wen Yu-Ming, Liu Hua, Zhao Hong-Wei

机构信息

Department of Oral and Maxillofacial Surgery, West China College of Stomatology, Sichuan University, Chengdu 610041, PR China.

出版信息

Oral Oncol. 2008 Feb;44(2):187-92. doi: 10.1016/j.oraloncology.2007.01.016. Epub 2007 Apr 5.

Abstract

In our study, 3461 cases of salivary gland tumor treated between 1955 and 2002 at West China Stomatology Hospital of Sichuan University were retrospectively analyzed, and compared with the previous reports. Measures such as age, tumor location, tumor histological type, and the nature of the growth (benign or malignant) were recorded at the same time. The findings are as follows: the average ages of salivary gland tumor patients were 41.38 years for the benign cases and 45.20 for the malignant ones; the male:female ratio was 0. 99:1 in the benign cases and 1.34:1 in the malignant ones; primary tumors were mostly in the parotid gland, palate and submandibular gland in sequence. Pleomorphic adenoma was the most frequent benign tumor followed by Warthin's tumor and basal cell adenoma, whereas mucoepidermoid carcinoma, adenoid cystic carcinoma and adenocarcinoma not otherwise specified were the most frequent malignant tumors. The incidence of salivary gland tumors increased with age. The male:female ratio of malignant tumors was higher than that of benign ones. The parotid gland and palate were the most common locations of salivary gland tumors. Pleomorphic adenoma and mucoepidermoid carcinoma were the most frequent benign and malignant tumors, respectively.

摘要

在我们的研究中,对1955年至2002年期间在四川大学华西口腔医院接受治疗的3461例涎腺肿瘤病例进行了回顾性分析,并与先前的报告进行了比较。同时记录了年龄、肿瘤位置、肿瘤组织学类型以及生长性质(良性或恶性)等指标。结果如下:涎腺肿瘤患者中,良性病例的平均年龄为41.38岁,恶性病例为45.20岁;良性病例的男女比例为0.99:1,恶性病例为1.34:1;原发肿瘤依次多位于腮腺、腭部和下颌下腺。多形性腺瘤是最常见的良性肿瘤,其次是沃辛瘤和基底细胞腺瘤,而黏液表皮样癌、腺样囊性癌和未另行规定的腺癌是最常见的恶性肿瘤。涎腺肿瘤的发病率随年龄增长而增加。恶性肿瘤的男女比例高于良性肿瘤。腮腺和腭部是涎腺肿瘤最常见的部位。多形性腺瘤和黏液表皮样癌分别是最常见的良性和恶性肿瘤。

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