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通过电疼痛刺激预测术后疼痛

Prediction of post-operative pain by an electrical pain stimulus.

作者信息

Nielsen P R, Nørgaard L, Rasmussen L S, Kehlet H

机构信息

Department of Anaesthesia, Centre of Head and Orthopaedics, Rigshospitalet, University of Copenhagen, Blegdamsvej 9, DK-2100 Copenhagen, Denmark.

出版信息

Acta Anaesthesiol Scand. 2007 May;51(5):582-6. doi: 10.1111/j.1399-6576.2007.01271.x.

Abstract

BACKGROUND

Treatment of post-operative pain is still a significant problem. Recently, interest has focused on pre-operative identification of patients who may experience severe post-operative pain in order to offer a more aggressive analgesic treatment. The nociceptive stimulation methods have included heat injury and pressure algometry. A simple method, Pain Matcher (PM), using electrical stimulation, is validated for pain assessment, but has not been evaluated as a tool for prediction of post-operative pain. Our aim was to assess the predictive value of pre-caesarean section pain threshold on intensity of post-caesarean section pain using the PM.

PATIENTS AND METHODS

Thirty-nine healthy women scheduled for elective caesarean section were studied. The anaesthetic/analgesic procedures included spinal anaesthesia, paracetamol, diclofenac, controlled-release (CR) oxycodone and morphine on request. Pre-operatively, the sensory and pain thresholds were measured using the PM. Post-operatively, a midwife, blinded for pre-caesarean pain threshold assessments, assessed the pain at rest and during mobilization every 12 h for 2 days. Consumption of analgesics was also recorded.

RESULTS

Pre-operative pain threshold correlated significantly with post-caesarean pain score (VAS) at rest and mobilization: [Spearman's rho =-0.65 (-0.30 to -0.75), P < 0.01] and [Spearman's rho =-0.52 (-0.23 to -0.72), P < 0.01], respectively. There was no significant correlation between pre-operative PM assessment of sensory threshold and post-operative pain.

CONCLUSION

Electrical pain threshold before caesarean section seems to predict the intensity of post-operative pain. This method may be used as a screening tool to identify patients at high risk of post-operative pain.

摘要

背景

术后疼痛的治疗仍是一个重大问题。近来,人们的关注点集中在术前识别可能经历严重术后疼痛的患者,以便提供更积极的镇痛治疗。伤害性刺激方法包括热损伤和压力痛觉测定法。一种使用电刺激的简单方法——疼痛匹配器(PM)已被验证可用于疼痛评估,但尚未作为预测术后疼痛的工具进行评估。我们的目的是使用PM评估剖宫产术前疼痛阈值对剖宫产术后疼痛强度的预测价值。

患者与方法

对39名计划进行择期剖宫产的健康女性进行了研究。麻醉/镇痛程序包括脊髓麻醉、对乙酰氨基酚、双氯芬酸、按需使用的控释(CR)羟考酮和吗啡。术前,使用PM测量感觉阈值和疼痛阈值。术后,一名对剖宫产术前疼痛阈值评估不知情的助产士,在2天内每12小时评估一次静息和活动时的疼痛情况。还记录了镇痛药的消耗量。

结果

术前疼痛阈值与剖宫产术后静息和活动时的疼痛评分(视觉模拟评分法)显著相关:[斯皮尔曼等级相关系数=-0.65(-0.30至-0.75),P<0.01]和[斯皮尔曼等级相关系数=-0.52(-0.23至-0.72),P<0.01]。术前PM评估的感觉阈值与术后疼痛之间无显著相关性。

结论

剖宫产术前的电疼痛阈值似乎可以预测术后疼痛的强度。该方法可作为一种筛查工具,用于识别术后疼痛高危患者。

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