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一种含银抗菌敷料可缩短小儿烧伤患者的住院时间。

A silver impregnated antimicrobial dressing reduces hospital length of stay for pediatric patients with burns.

作者信息

Paddock Heather N, Fabia Renata, Giles Shelia, Hayes John, Lowell Wendi, Besner Gail E

机构信息

Department of Pediatric Surgery, Children's Hospital, 700 Children's Drive, Columbus, Ohio 43205, USA.

出版信息

J Burn Care Res. 2007 May-Jun;28(3):409-11. doi: 10.1097/BCR.0B013E318053D2B9.

Abstract

We sought to study whether the application of a novel silver impregnated antimicrobial dressing (Aquacel Ag, ConvaTec, Princeton, NJ) affects the hospital length of stay in pediatric patients with partial-thickness burns. A retrospective review of Burn Registry Data from a large children's hospital burn unit was conducted to answer this question. Pediatric patients admitted with partial-thickness burns treated with Aquacel Ag from January 2005 through August 2005 were included in the study (n = 39). The comparison group of patients treated with silver sulfadiazine (SSD; Par Pharmeceuticals, Woodcliff, NJ) cream was matched for age and %TBSA burned from the same time period the previous year (n = 40). Analysis was conducted for intent to treat. Mean length of stay for control patients treated with SSD was significantly longer (8.36 days) compared with Aquacel Ag-treated patients (4.48 days; p = .002, t-test for unequal variances). Length of stay for both groups was significantly associated with %TBSA burned (p < .001, r2 = .38). Post-hoc analysis controlling for %TBSA burned revealed an adjusted mean length of stay for the control group that was longer than that of the Aquacel Ag group (5.9 days vs. 3.8 days, respectively). These data confirm that application of a new burn dressing (Aquacel Ag) reduces hospital length of stay. Reduction in the complexity and number of dressing changes needed with use of Aquacel Ag, in combination with significantly reduced length of stay, should result in a significant cost savings in the care of this patient population.

摘要

我们试图研究一种新型含银抗菌敷料(Aquacel Ag,康维德公司,新泽西州普林斯顿)的应用是否会影响小儿浅度烧伤患者的住院时间。为回答这个问题,我们对一家大型儿童医院烧伤科的烧伤登记数据进行了回顾性研究。纳入研究的是2005年1月至2005年8月期间使用Aquacel Ag治疗的小儿浅度烧伤患者(n = 39)。使用磺胺嘧啶银(SSD;Par制药公司,新泽西州伍德克利夫)乳膏治疗的患者作为对照组,与上一年同期烧伤面积百分比和年龄相匹配(n = 40)。进行意向性分析。与使用Aquacel Ag治疗的患者相比,使用SSD治疗的对照组患者平均住院时间显著更长(8.36天)(4.48天;p = 0.002,方差不齐的t检验)。两组的住院时间均与烧伤面积百分比显著相关(p < 0.001,r2 = 0.38)。在控制烧伤面积百分比的事后分析中发现,对照组的调整后平均住院时间长于Aquacel Ag组(分别为5.9天和3.8天)。这些数据证实,应用一种新的烧伤敷料(Aquacel Ag)可缩短住院时间。使用Aquacel Ag可减少换药的复杂性和次数,同时显著缩短住院时间,这应该会在该患者群体的护理中显著节省成本。

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