一项依据四套诊断标准对阿斯伯格综合征进行的流行病学与诊断研究。
An epidemiological and diagnostic study of Asperger syndrome according to four sets of diagnostic criteria.
作者信息
Mattila Marja-Leena, Kielinen Marko, Jussila Katja, Linna Sirkka-Liisa, Bloigu Risto, Ebeling Hanna, Moilanen Irma
机构信息
All of the authors are with the Clinic of Child Psychiatry, University and University Hospital of Oulu, Finland, with the exception of Mr. Bloigu, who is with the Medical Faculty, University of Oulu, Finland.
All of the authors are with the Clinic of Child Psychiatry, University and University Hospital of Oulu, Finland, with the exception of Mr. Bloigu, who is with the Medical Faculty, University of Oulu, Finland.
出版信息
J Am Acad Child Adolesc Psychiatry. 2007 May;46(5):636-646. doi: 10.1097/chi.0b013e318033ff42.
OBJECTIVE
This study evaluated the diagnostic process and prevalence rates of Asperger syndrome (AS) according to the DSM-IV, ICD-10, and criteria developed by Gillberg and Gillberg and by Szatmari and colleagues and clarified confusion about AS.
METHOD
An epidemiological study of 5,484 eight-year-old children in Finland, 4,422 (80.6%) of whom rated on the high-functioning Autism Spectrum Screening Questionnaire by parents and/or teacher, 125 of them screened and 110 examined by using structured interview, semistructured observation, IQ measurement, school day observation, and patient records. Diagnoses were performed by following the DSM-IV, ICD-10, and criteria developed by Gillberg and Gillberg and by Szatmari and colleagues in detail.
RESULTS
The prevalence rates per 1,000 were 2.5 according to the DSM-IV, 2.9 to ICD-10, 2.7 to Gillberg and Gillberg's criteria, and 1.6 to the criteria of Szatmari et al.
CONCLUSIONS
The results emphasize the need to reconsider the diagnostic criteria of AS. The importance of multi-informant sources came up, and the need of several informants was highlighted, especially when diagnosing the broader pervasive developmental disorders.
目的
本研究根据《精神疾病诊断与统计手册》第四版（DSM-IV）、《国际疾病分类》第十版（ICD-10）以及吉尔伯格和吉尔伯格制定的标准以及萨特马里及其同事制定的标准，评估了阿斯伯格综合征（AS）的诊断过程和患病率，并澄清了关于AS的混淆之处。
方法
对芬兰5484名8岁儿童进行了一项流行病学研究，其中4422名（80.6%）儿童由家长和/或教师通过高功能自闭症谱系筛查问卷进行评分，对其中125名儿童进行了筛查，并通过结构化访谈、半结构化观察、智商测量、学校日常观察和患者记录对110名儿童进行了检查。诊断是按照DSM-IV、ICD-10以及吉尔伯格和吉尔伯格制定的标准以及萨特马里及其同事制定的标准详细进行的。
结果
每1000人中的患病率，根据DSM-IV为2.5，根据ICD-10为2.9，根据吉尔伯格和吉尔伯格的标准为2.7，根据萨特马里等人的标准为1.6。
结论
结果强调需要重新考虑AS的诊断标准。多信息来源的重要性显现出来，突出了需要多个信息提供者，尤其是在诊断更广泛的广泛性发育障碍时。
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