Piekarski J H, Jereczek-Fossa B A, Nejc D, Pluta P, Szymczak W, Sek P, Bilski A, Gottwald L, Jeziorski A
Department of Surgical Oncology, Chair of Oncology, Medical University of Lodz, Lodz, Poland.
Int J Gynecol Cancer. 2008 Jan-Feb;18(1):66-70. doi: 10.1111/j.1525-1438.2007.00954.x. Epub 2007 Apr 26.
Analysis of the clinical course of patients with postirradiation rectovaginal fistula after fecal diversion. The studied group included 17 women with postirradiation rectovaginal fistula who underwent fecal diversion as a sole mode of treatment, between January 1987 and December 2002, in our department. All patients were subjected to radiotherapy due to cancer of the uterine cervix, administered 5-107 months before the fistula appearance (mean, 22.9 months). In 3 of 17 patients (18%), spontaneous closure of fistula was observed after 5, 6, and 9 months, respectively, from fecal diversion. Closure was confirmed by endoscopy. Length of follow-up after fecal diversion ranged from 0.5 to 122 months. The actuarial probability of spontaneous closure of postradiotherapy rectovaginal fistula was 0.24 at 9 months of follow-up and then remained stable thereafter. In conclusion, colostomy alone gives hardly a chance for closure of the postradiotherapy rectovaginal fistula. Additional surgical measures are necessary.
粪便转流术后放射性直肠阴道瘘患者的临床病程分析。研究组包括1987年1月至2002年12月期间在我科接受粪便转流作为唯一治疗方式的17例放射性直肠阴道瘘女性患者。所有患者均因子宫颈癌接受放疗,在瘘管出现前5 - 107个月(平均22.9个月)进行。17例患者中有3例(18%)在粪便转流后分别于5、6和9个月观察到瘘管自发闭合。通过内镜检查确认闭合。粪便转流后的随访时间为0.5至122个月。放疗后直肠阴道瘘自发闭合的精算概率在随访9个月时为0.24,此后保持稳定。总之,单纯结肠造口术几乎没有机会使放疗后直肠阴道瘘闭合。需要采取额外的手术措施。