[吉特曼综合征患者的妊娠：一例病例报告及文献复习]

[Pregnancy in a patient with Gitelman syndrome: a case report and review of literature].

作者信息

Ducarme G, Davitian C, Uzan M, Belenfant X, Poncelet C

机构信息

Service de Gynécologie et d'Obstétrique, CHU Jean-Verdier, APHP, Avenue du 14-Juillet, Bondy Cedex, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2007 May;36(3):310-3. doi: 10.1016/j.jgyn.2006.10.004. Epub 2006 Dec 27.

DOI:10.1016/j.jgyn.2006.10.004

PMID:17466223

Abstract

Gitelman syndrome (GS) is a tubulopathy characterized by hypokaliemia, hypomagnesiemia, metabolic alkalosis and hypocalciuria. We report a case of a 33-year-old pregnant woman with Gitelman Syndrome. Oral potassium chloride and magnesium citrate were prescribed and the course of the pregnancy was uneventful with vaginal delivery at term. The impact of GS on the physiologic adaptations to pregnancy is not well-known, with few reports to date. Monitoring of serum potassium and magnesium levels with supplementation, amniotic fluid and fetal growth is required to prevent obstetrical and fetal complications in a patient with GS.

摘要

吉特林综合征（GS）是一种肾小管疾病，其特征为低钾血症、低镁血症、代谢性碱中毒和低钙尿症。我们报告一例33岁患有吉特林综合征的孕妇。给予口服氯化钾和枸橼酸镁，孕期过程顺利，足月顺产。GS对妊娠生理适应的影响尚不清楚，迄今为止报道很少。对于GS患者，需要监测血清钾和镁水平并进行补充，同时监测羊水和胎儿生长情况，以预防产科和胎儿并发症。