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治疗骨质疏松性椎体骨折的微创技术

Minimally invasive techniques for the treatment of osteoporotic vertebral fractures.

作者信息

Manson Neil A, Phillips Frank M

机构信息

Midwest Orthopaedics at Rush, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

Instr Course Lect. 2007;56:273-85.

Abstract

Osteoporotic vertebral compression fractures are a leading cause of disability and morbidity in the elderly. The consequences of these fractures include pain, progressive vertebral collapse with resultant spinal kyphosis, and systemic manifestations. Nonsurgical measures have proved unsuccessful in a portion of this population and for this group, minimally invasive vertebral augmentation can be beneficial. Vertebroplasty is designed to address vertebral fracture pain. It involves percutaneous injection of polymethylmethacrylate (PMMA) directly into a fractured vertebral body with the goals of pain relief and prevention of further collapse of the fractured vertebra. Kyphoplasty is designed to address the kyphotic deformity as well as the fracture pain. It involves the percutaneous insertion of an inflatable bone tamp into a fractured vertebral body. Bone tamp inflation works to elevate the end plates and create a cavity to be filled with PMMA with the goals of pain relief, restoration of vertebral body height, and reduced kyphotic deformity. Optimizing surgical technique can improve outcomes and decrease complication rates, and decrease radiation exposure to the patient and surgical team. Obtaining a biopsy prior to cement injection has proved efficacious and may result in the diagnosis of occult pathology underlying a seemingly routine vertebral fracture. As competence and surgical success are acquired, the indications will continue to expand to encompass more challenging pathologies. Recently, vertebral augmentation during spinal decompression and instrumented fusion for burst fracture with neurologic insult has been reported to be successful.

摘要

骨质疏松性椎体压缩骨折是老年人致残和发病的主要原因。这些骨折的后果包括疼痛、椎体逐渐塌陷并导致脊柱后凸以及全身表现。事实证明,非手术措施对部分此类患者并不成功,对于这一群体而言,微创椎体强化术可能有益。椎体成形术旨在缓解椎体骨折疼痛。它包括经皮将聚甲基丙烯酸甲酯(PMMA)直接注入骨折椎体,目的是缓解疼痛并防止骨折椎体进一步塌陷。后凸成形术旨在解决后凸畸形以及骨折疼痛。它包括经皮将可膨胀骨扩张器插入骨折椎体。骨扩张器充气可抬高终板并形成一个用于填充PMMA的腔隙,目的是缓解疼痛、恢复椎体高度并减轻后凸畸形。优化手术技术可改善手术效果并降低并发症发生率,同时减少患者和手术团队所受的辐射暴露。在注入骨水泥前进行活检已被证明是有效的,并可能导致对看似常规椎体骨折背后隐匿病理情况的诊断。随着技术水平和手术成功率的提高,适应症将继续扩大,以涵盖更具挑战性的病理情况。最近,有报道称在脊柱减压和器械融合治疗伴有神经损伤的爆裂骨折过程中进行椎体强化术取得了成功。

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