Katory M, Tang C L, Koh W L, Fook-Chong S M C, Loi T T, Ooi B S, Ho K S, Eu K W
Department of Colorectal Surgery, Singapore General Hospital, Singapore.
Colorectal Dis. 2008 Feb;10(2):165-9. doi: 10.1111/j.1463-1318.2007.01265.x. Epub 2007 May 16.
High anterior resection (HAR) for colorectal cancer is traditionally performed with routine mobilization of the splenic flexure. This is a retrospective review of mortality and morbidity following HAR in which the splenic flexure has been preserved.
From a prospective database, all patients who had undergone elective HAR for colorectal cancer between 1999 and 2005 were identified. Morbidity, mortality, pathology and survival data for patients having HAR with and without splenic flexure mobilization were analysed.
A total of 707 patients were identified. Five hundred and thirty-one had HAR with preservation of the splenic flexure. In these patients outcome was: anastomotic leak (0.4%), wound infection (3.6%), anastomotic stricture (0.4%) and 30-day mortality (0.9%). No statistical significant difference was found for postoperative morbidity (P = 0.1926), 30-day mortality (P =0.3285), lymph node harvest (P = 0.2127) or survival (P = 0.1457) compared with patients in whom the splenic flexure was mobilized. Longitudinal resection margins were greater following HAR with splenic flexure mobilization (P < 0.0001).
No morbidity, oncological or survival disadvantage in performing splenic flexure preserving HAR was found.
结直肠癌高位前切除术(HAR)传统上需常规游离脾曲。本文是一项关于保留脾曲的HAR术后死亡率和发病率的回顾性研究。
从一个前瞻性数据库中,确定了1999年至2005年间所有接受择期结直肠癌HAR的患者。分析了行HAR时游离或未游离脾曲患者的发病率、死亡率、病理及生存数据。
共确定707例患者。其中531例行保留脾曲的HAR。这些患者的结局为:吻合口漏(0.4%)、伤口感染(3.6%)、吻合口狭窄(0.4%)和30天死亡率(0.9%)。与游离脾曲的患者相比,术后发病率(P = 0.1926)、30天死亡率(P = 0.3285)、淋巴结清扫数(P = 0.2127)或生存率(P = 0.1457)均无统计学显著差异。游离脾曲的HAR术后纵向切缘更大(P < 0.0001)。
未发现保留脾曲的HAR在发病率、肿瘤学或生存方面存在劣势。