一种使用单离心泵的新型搏动式全人工心脏。

A new pulsatile total artificial heart using a single centrifugal pump.

作者信息

Imachi K, Chinzei T, Abe Y, Mabuchi K, Imanishi K, Yonezawa T, Kouno A, Ono T, Atsumi K, Isoyama T

机构信息

Institute of Medical Electronics, Faculty of Medicine, University of Tokyo, Japan.

出版信息

ASAIO Trans. 1991 Jul-Sep;37(3):M242-3.

PMID:1751129

Abstract

A new pulsatile total artificial heart (TAH) system, combining a single centrifugal pump (CFP) with two three-way valves, was developed. One port of each three-way valve was connected to the inlet and outlet of a CFP, respectively. The other two ports of each valve ware connected to the right and left atrium, pulmonary artery, and aorta. The CFP can perfuse the pulmonary and systemic circulation alternately with pulsatile flow. A prototype system composed of a Sarns' CFP and solenoid valves was connected to a mock circulatory system resulting in 1) a pulsatile TAH that could be produced with a single CFP, 2) 5 L/min of pulsatile output with a normal flow wave form that can be obtained alternately on the right and left side by switching the solenoid valves, and 3) flow balance between the left and the right that could be controlled easily by the length of switching duration. This new system could be miniaturized and is feasible for a totally implantable TAH.

摘要

一种新型搏动式全人工心脏（TAH）系统被研发出来，它将一个单离心式泵（CFP）与两个三通阀相结合。每个三通阀的一个端口分别连接到CFP的入口和出口。每个阀的另外两个端口分别连接到右心房、左心房、肺动脉和主动脉。CFP能够以搏动血流交替灌注肺循环和体循环。一个由Sarns的CFP和电磁阀组成的原型系统连接到模拟循环系统，结果显示：1）用单个CFP就能制造出搏动式TAH；2）能产生5升/分钟的搏动输出，具有正常的血流波形，通过切换电磁阀可在右侧和左侧交替获得；3）左右两侧的血流平衡可通过切换持续时间的长短轻松控制。这种新系统可以小型化，对于完全植入式TAH是可行的。