高频心电图分析在预测腺苷心肌灌注成像期间可逆性灌注缺损方面的能力。
High-frequency electrocardiogram analysis in the ability to predict reversible perfusion defects during adenosine myocardial perfusion imaging.
作者信息
Trägårdh Elin, Schlegel Todd T, Carlsson Marcus, Pettersson Jonas, Nilsson Klas, Pahlm Olle
机构信息
Department of Clinical Physiology, Lund University Hospital, Lund, Sweden.
出版信息
J Electrocardiol. 2007 Nov-Dec;40(6):510-4. doi: 10.1016/j.jelectrocard.2007.03.242. Epub 2007 May 24.
BACKGROUND
A previous study has shown that analysis of high-frequency QRS components (HF-QRS) is highly sensitive and reasonably specific for detecting reversible perfusion defects on adenosine myocardial perfusion imaging (MPI) scans. The purpose of the present study was to try to reproduce those findings.
METHODS
Twelve-lead high-resolution electrocardiogram recordings were obtained from 100 patients before (baseline) and during adenosine (99m)Tc-tetrofosmin MPI tests. The HF-QRS were analyzed regarding morphology and changes in root mean square voltages from before the adenosine infusion to peak infusion.
RESULTS
The best area under the curve (AUC) was found in supine patients (AUC = 0.736) in a combination of morphology and root mean square changes. None of the measurements, however, were statistically better than tossing a coin (AUC = 0.5).
CONCLUSION
Analysis of HF-QRS was not significantly better than tossing a coin for determining reversible perfusion defects on MPI scans.
背景
先前的一项研究表明，高频QRS波成分（HF-QRS）分析对于检测腺苷心肌灌注成像（MPI）扫描中的可逆灌注缺损具有高度敏感性和合理的特异性。本研究的目的是尝试重现这些发现。
方法
在100例患者进行腺苷（99m）锝替曲膦MPI检查之前（基线）和检查期间，获取其12导联高分辨率心电图记录。分析HF-QRS的形态以及从腺苷输注前到输注峰值期间均方根电压的变化。
结果
在仰卧位患者中，形态学和均方根变化相结合时曲线下面积（AUC）最佳（AUC = 0.736）。然而，没有一项测量在统计学上比抛硬币更好（AUC = 0.5）。
结论
对于在MPI扫描中确定可逆灌注缺损，HF-QRS分析并不比抛硬币显著更好。
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