一份前列腺癌放射晚期毒性问卷的心理测量学特性
Psychometric properties of a prostate cancer radiation late toxicity questionnaire.
作者信息
Rodrigues George, Bauman Glenn, Lock Michael, D'Souza David, Mahon Jeff
机构信息
Department of Oncology, University of Western Ontario, London, Ontario, Canada.
出版信息
Health Qual Life Outcomes. 2007 May 31;5:29. doi: 10.1186/1477-7525-5-29.
BACKGROUND
To construct a short prostate cancer radiation late toxicity (PCRT) questionnaire with health-related quality-of-life (HRQoL) domains.
METHODS
The PCRT was developed by item generation, questionnaire construction (n = 7 experts, n = 8 focus group patients), pilot testing (n = 37), item reduction (n = 100), reliability testing (n = 237), and validity testing (n = 274).
RESULTS
Reliability of the three item-reduced subscales demonstrated intraclass correlation coefficients (CC) of 0.811 (GU), 0.842 (GI), and 0.740 (sexual). Discriminant validity demonstrated Pearson CC of 0.449 (GU-GI), 0.200 (sexual-GU), and 0.09 (sexual-GI). Content validity correlations between PCRT-PCQoL were 0.35-0.78, PCRT-FACT-G(c) were 0.19-0.39, and PCRT-SF-36(R) were 0.03-0.34.
CONCLUSION
We successfully generated a PCRT HRQoL questionnaire including subscales with very good psychometric properties.
背景
构建一份包含健康相关生活质量（HRQoL）领域的简短前列腺癌放疗晚期毒性（PCRT）问卷。
方法
PCRT通过条目生成、问卷构建（7名专家，8组焦点组患者）、预试验（37例）、条目删减（100例）、信度测试（237例）和效度测试（274例）来制定。
结果
三个删减条目后的子量表的信度显示组内相关系数（CC）分别为：泌尿生殖系统（GU）0.811、胃肠道（GI）0.842、性功能0.740。判别效度显示Pearson相关系数分别为：GU与GI为0.449、性功能与GU为0.200、性功能与GI为0.09。PCRT与前列腺癌生活质量量表（PCQoL）的内容效度相关性为0.35 - 0.78，PCRT与癌症治疗功能评价量表通用版（FACT - G(c)）为0.19 - 0.39，PCRT与简短健康调查量表（SF - 36(R)）为0.03 - 0.34。
结论
我们成功生成了一份PCRT HRQoL问卷，其包含的子量表具有非常好的心理测量学特性。
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