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黑人和白人心脏康复患者的二级预防结果。

Secondary prevention outcomes among black and white cardiac rehabilitation patients.

作者信息

Sanderson Bonnie K, Mirza Saema, Fry Rachel, Allison Jeroan J, Bittner Vera

机构信息

Division of Cardiovascular Disease, Preventive Cardiology, University of Alabama at Birmingham, AL 35294, USA.

出版信息

Am Heart J. 2007 Jun;153(6):980-6. doi: 10.1016/j.ahj.2007.03.020.

Abstract

BACKGROUND

Disparities in coronary heart disease and related risk factors persist. It is unknown if cardiac rehabilitation (CR) narrows the gap in risk factor control between black and white patients. Thus, we compared baseline characteristics and secondary prevention outcomes between black and white CR patients.

METHODS

Data from patient records (n = 616, mean age 62 +/- 10 years, 29% women, 25% black) collected between January 1996 and June 2006 were examined. Comparisons were made between Blacks and Whites for baseline characteristics, changes in secondary prevention measures during CR, and the proportion of patients at treatment goals before and after CR. General linear regression modeling was used to determine the effect of race/ethnicity on outcomes.

RESULTS

At baseline, Blacks had more hypertension and diabetes and more adverse measures for blood pressure, low-density lipoprotein and non-high-density lipoprotein cholesterol (non-HDL-C), hemoglobin A1c, 6-minute walk distance, and Short-Form Health Survey (SF-36) physical component score. At CR completion, improvement (P < .05) was achieved among whites in all measures except for HDL-C and systolic blood pressure. Among Blacks, improvement did not reach significance for HDL-C, body mass index, waist circumference, and hemoglobin A1c (when diabetes was present). When adjusting for age, gender, number of sessions attended, and baseline measure, Whites improved more than Blacks in 6-minute walk distance, self-reported physical activity, body mass index, waist circumference, low-density lipoprotein cholesterol, and hemoglobin A1c (all P < .05).

CONCLUSION

Blacks entered CR with more adverse risk factor measures compared with Whites. Although both groups gained secondary prevention benefits, the degree of improvement was less for Blacks than Whites, and this was especially evident among black women.

摘要

背景

冠心病及相关危险因素的差异依然存在。心脏康复(CR)是否能缩小黑人和白人患者在危险因素控制方面的差距尚不清楚。因此,我们比较了黑人和白人CR患者的基线特征和二级预防结果。

方法

对1996年1月至2006年6月收集的患者记录数据(n = 616,平均年龄62±10岁,29%为女性,25%为黑人)进行了检查。比较了黑人和白人的基线特征、CR期间二级预防措施的变化以及CR前后达到治疗目标的患者比例。采用一般线性回归模型确定种族/族裔对结果的影响。

结果

在基线时,黑人患高血压和糖尿病的比例更高,在血压、低密度脂蛋白和非高密度脂蛋白胆固醇(非HDL-C)、糖化血红蛋白、6分钟步行距离和简短健康调查问卷(SF-36)身体成分评分方面有更多不良指标。在CR结束时,除HDL-C和收缩压外,白人在所有指标上均有改善(P < 0.05)。在黑人中,HDL-C、体重指数、腰围和糖化血红蛋白(糖尿病患者)的改善未达到显著水平。在调整年龄、性别、参加疗程数和基线指标后,白人在6分钟步行距离、自我报告的身体活动、体重指数、腰围、低密度脂蛋白胆固醇和糖化血红蛋白方面的改善比黑人更大(均P < 0.05)。

结论

与白人相比,黑人进入CR时的危险因素指标更差。尽管两组都获得了二级预防益处,但黑人的改善程度低于白人,这在黑人女性中尤为明显。

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