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退伍军人事务部医院与部分大学医学中心经风险调整后的术后30天死亡率和发病率比较:女性血管外科手术

Comparison of risk-adjusted 30-day postoperative mortality and morbidity in Department of Veterans Affairs hospitals and selected university medical centers: vascular surgical operations in women.

作者信息

Johnson Robert G, Wittgen Catherine M, Hutter Matthew M, Henderson William G, Mosca Cecilia, Khuri Shukri F

机构信息

Department of Surgery, Saint Louis University, St Louis, MO 63110, USA.

出版信息

J Am Coll Surg. 2007 Jun;204(6):1137-46. doi: 10.1016/j.jamcollsurg.2007.02.059.

Abstract

BACKGROUND

Women with peripheral vascular disease requiring vascular operations are less well studied than their male counterparts. The surgical outcomes of female vascular patients in the Department of Veterans Affairs (VA) and private sector hospitals have not previously been compared, and their preoperative risk profile, postoperative morbidity, and mortality need to be better elucidated.

STUDY DESIGN

Patients undergoing vascular operations at 14 private sector and 128 VA hospitals, from October 2001 through September 2004, had their preoperative characteristics, operative data, and 30-day postoperative morbidity and mortality compared, as part of the Patient Safety in Surgery (PSS) Study. Logistic regression analysis was performed to develop predictive models for morbidity and mortality, which allowed for a comparison of risk-adjusted outcomes between the two hospital groups.

RESULTS

There were 458 vascular surgical operations performed in women in the VA, and 3,535 vascular operations were performed in women in the private sector. Eighteen of 45 preoperative comorbidities and laboratory variables differed considerably between the institutions, and 16 of 18 were adverse among the private sector patients. The unadjusted 30-day mortality rate was higher in the private sector compared with the VA (5.2% versus 2.4%, p=0.008); the unadjusted morbidity rate was higher in the private sector compared with the VA sector (23.4% versus 13.3%, p < 0.0001). After risk adjustment, there was no marked difference between the VA and the private sector in mortality (p=0.12), but the difference in morbidity rates remained pronounced, with an odds ratio of 0.60 for VA versus private sector (95% CI=0.44, 0.81).

CONCLUSIONS

Compared with their VA counterparts, women undergoing vascular operations at private sector hospitals had a higher incidence of preoperative comorbidities; after risk adjustment, mortality did not differ substantially. Despite risk adjustment, the incidence of postoperative morbidity in the VA patients was considerably lower, suggesting unidentified differences in the hospital populations, their processes of care, or both.

摘要

背景

与男性外周血管疾病患者相比,需要进行血管手术的女性患者的相关研究较少。退伍军人事务部(VA)医院和私立医院中女性血管疾病患者的手术结果此前尚未进行比较,她们的术前风险状况、术后发病率和死亡率需要进一步阐明。

研究设计

作为手术患者安全(PSS)研究的一部分,对2001年10月至2004年9月期间在14家私立医院和128家VA医院接受血管手术的患者的术前特征、手术数据以及术后30天的发病率和死亡率进行了比较。进行了逻辑回归分析以建立发病率和死亡率的预测模型,从而能够比较两个医院组之间经风险调整后的结果。

结果

VA医院中有458例女性接受了血管手术,私立医院中有3535例女性接受了血管手术。45种术前合并症和实验室变量中的18种在不同机构之间存在显著差异,其中18种中的16种在私立医院患者中更为不利。私立医院未经调整的30天死亡率高于VA医院(5.2%对2.4%,p = 0.008);私立医院未经调整的发病率高于VA医院(23.4%对13.3%,p < 0.0001)。经过风险调整后,VA医院和私立医院在死亡率方面没有显著差异(p = 0.12),但发病率差异仍然显著,VA医院与私立医院的比值比为0.60(95%可信区间 = 0.44, 0.81)。

结论

与VA医院的女性患者相比,在私立医院接受血管手术的女性术前合并症的发生率更高;经过风险调整后,死亡率没有实质性差异。尽管进行了风险调整,但VA医院患者术后发病率的发生率要低得多,这表明在医院人群、护理过程或两者方面存在未明确的差异。

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