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孕13周诊断出的宫内合并宫颈妊娠:哪种治疗方式更可行且成功?

A combined intrauterine and cervical pregnancy diagnosed in the 13th gestational week: which type of management is more feasible and successful?

作者信息

Fruscalzo Arrigo, Mai Marion, Löbbeke Kay, Marchesoni Diego, Klockenbusch Walter

机构信息

Department of Obstetrics and Gynaecology, University of Udine, Udine, Italy.

出版信息

Fertil Steril. 2008 Feb;89(2):456.e13-6. doi: 10.1016/j.fertnstert.2007.03.072. Epub 2007 Jun 11.

Abstract

OBJECTIVE

To present a case of a simultaneous nonviable cervical pregnancy and viable intrauterine pregnancy diagnosed in the 13th gestational week and to discuss the possible therapeutic options.

DESIGN

Case report.

SETTING

University hospital of Münster, Germany.

PATIENT(S): A 40-year-old woman who had undergone IVF-embryo transfer because of previous surgical sterilization.

INTERVENTION(S): Hospitalization with observation, expecting spontaneous expulsion of the nonviable cervical pregnancy.

MAIN OUTCOME MEASURE(S): Intrauterine pregnancy preservation; maternal morbidity and mortality.

RESULT(S): Three weeks after diagnosis, the expulsion of a nonviable cervical pregnancy occurred. It was accompanied by pronounced cervical hemorrhage, conservatively managed with cervical curettage and stitches under general anesthesia. Unfortunately, a few hours later, spontaneous abortion of the intrauterine pregnancy occurred. Blood transfusion was postoperatively avoided, although pronounced anemia was detected (7.3 g/dL). The patient was than discharged 3 days later.

CONCLUSION(S): Combined intrauterine and cervical pregnancy is a remote but possible event, particularly after assisted reproductive technology (ART) procedures. Its management should be carefully evaluated, according to the clinical situation and patient's desire. In case of nonviable cervical pregnancy, if a noninterventional approach is chosen, and especially when gestational age is advanced, hospitalization should be recommended in an attempt to prevent possible critical hemorrhagic complications due to cervical pregnancy expulsion.

摘要

目的

介绍一例在孕13周时诊断出的同时存在的不可存活宫颈妊娠和可存活宫内妊娠病例,并讨论可能的治疗选择。

设计

病例报告。

地点

德国明斯特大学医院。

患者

一名40岁女性,因先前手术绝育而接受体外受精 - 胚胎移植。

干预措施

住院观察,期待不可存活的宫颈妊娠自然排出。

主要观察指标

宫内妊娠的保留情况;孕产妇发病率和死亡率。

结果

诊断后三周,不可存活的宫颈妊娠排出。伴有明显的宫颈出血,在全身麻醉下通过宫颈刮宫和缝合进行保守处理。不幸的是,几小时后,宫内妊娠发生自然流产。尽管检测到明显贫血(7.3 g/dL),术后仍避免了输血。患者于三天后出院。

结论

宫内和宫颈联合妊娠是一种罕见但可能发生的情况,特别是在辅助生殖技术(ART)操作之后。应根据临床情况和患者意愿仔细评估其管理方法。对于不可存活的宫颈妊娠,如果选择非介入性方法,尤其是在孕周较大时,建议住院以预防宫颈妊娠排出可能导致的严重出血并发症。

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