Gau Jen-Tzer, Acharya Utkarsh, Marx Tracy, Verne G Nicholas, Carlsen Wayne
Department of Geriatric Medicine/Gerontology, College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
J Am Med Dir Assoc. 2007 Jun;8(5):338-41. doi: 10.1016/j.jamda.2007.01.004. Epub 2007 May 3.
Persistent megacolon that results from frequent episodes of fecal impaction without adequate treatment is a rare and seldom reported condition in the elderly. This report discusses a 72-year-old white woman presenting with a large abdominal mass, who had at least 4 episodes of radiographically demonstrated fecal impaction over the previous year without adequate treatment. The patient required hospitalization for a bleeding rectal ulcer during the second episode of fecal impaction. Computed tomography (CT) scans on this admission revealed a dilated colon up to 16 x 14 cm in maximal dimensions extending over 30 cm, filled with massive fecal material. Several follow-up abdominal radiographs revealed a persistent megacolon after 10 months despite the absence of significant fecal material in the rectosigmoid colon. While multiple contributing factors were likely involved in her frequent fecal impactions, the clinical course of this case suggests that frequent fecal impactions without adequate treatment can lead to megacolon in high-risk patients. Clinicians should aggressively treat fecal impaction and monitor the adequacy of treatment with abdominal radiography in order to avoid significant complications. Complications and management of fecal impaction and the pathophysiology of megacolon in the literature are reviewed and discussed.
因频繁发生粪便嵌塞且未得到充分治疗而导致的持续性巨结肠在老年人中是一种罕见且鲜有报道的病症。本报告讨论了一名72岁的白人女性,她因腹部出现巨大肿块前来就诊,在过去一年中至少有4次经影像学证实的粪便嵌塞,但均未得到充分治疗。该患者在第二次粪便嵌塞期间因直肠溃疡出血而住院。此次入院时的计算机断层扫描(CT)显示,扩张的结肠最大尺寸达16×14厘米,长度超过30厘米,内充满大量粪便物质。后续的几次腹部X光片显示,尽管直肠乙状结肠内没有大量粪便物质,但10个月后仍存在持续性巨结肠。虽然她频繁发生粪便嵌塞可能涉及多种因素,但该病例的临床过程表明,对于高危患者,频繁的粪便嵌塞且未得到充分治疗可导致巨结肠。临床医生应积极治疗粪便嵌塞,并通过腹部X光检查监测治疗效果,以避免出现严重并发症。本文对文献中粪便嵌塞的并发症、治疗以及巨结肠的病理生理学进行了综述和讨论。