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骨质疏松症的二级预防:桡骨远端骨折后的钙、维生素D及双膦酸盐处方

Secondary prevention of osteoporosis: Calcium, Vitamin D and bisphosphonate prescribing following distal radial fracture.

作者信息

Talbot J C, Elener C, Praveen P, Shaw D L

机构信息

Department of Orthopaedic and Trauma Surgery, Bradford Teaching Hospitals NHS Trust, UK.

出版信息

Injury. 2007 Nov;38(11):1236-40. doi: 10.1016/j.injury.2007.03.004. Epub 2007 Jun 18.

Abstract

Over 200,000 osteoporotic fractures occur in the UK annually. Patients with fragility fractures are at highest risk of further fracture, though preventative treatment has been shown to reduce subsequent fracture incidence. We reviewed the pre- and post-fracture medication (via the PCTs and in-patient discharge letters) of all patients over 55 years who suffered a distal radial fracture between April 2003 and November 2004. Complete data was available for 175 patients (170 female): 95 were in-patients, 80 out-patients. Following distal radial fracture, calcium and Vitamin D was prescribed for 39 patients (22%), bisphosphonates to 16 patients (9%) and only 15 patients (8.5%) were referred for DEXA scanning. Higher rates of prescribing were seen in hospital, with over half of all in-patients started on fracture prevention treatment; however, less than a half of these patients continued to receive this medication in primary care. We believe, the results demonstrate a lack of health promotion opportunities to prevent future fracture, which is a common finding across healthcare systems nationally. Although there is clear focus and impetus for developing falls prevention services nationwide, this enthusiasm has not been translated across to bone health, despite the potential savings in terms of morbidity, mortality and healthcare costs. Important deficiencies in local services have been identified, particularly with respect to communication between secondary and primary care. This study has added weight to secure funding for a fracture liaison nurse in our institution; we suggest others follow suit and employ similarly dedicated personnel to ensure assessment and treatment for the prevention of further fractures.

摘要

英国每年发生超过20万例骨质疏松性骨折。脆性骨折患者再次骨折的风险最高,不过预防性治疗已被证明可降低后续骨折发生率。我们回顾了2003年4月至2004年11月期间所有55岁以上桡骨远端骨折患者骨折前后的用药情况(通过初级保健信托机构和住院出院信件)。175例患者(170例女性)有完整数据:95例为住院患者,80例为门诊患者。桡骨远端骨折后,39例患者(22%)被开具了钙和维生素D,16例患者(9%)被开具了双膦酸盐,只有15例患者(8.5%)被转诊进行双能X线吸收法扫描。在医院里开具药物的比例更高,超过一半的住院患者开始接受骨折预防治疗;然而,这些患者中不到一半在初级保健中继续接受这种药物治疗。我们认为,结果表明缺乏预防未来骨折的健康促进机会,这在全国医疗系统中是一个常见的发现。尽管全国范围内明确关注并推动了预防跌倒服务的发展,但这种热情尚未转化为骨骼健康方面的行动,尽管在发病率、死亡率和医疗成本方面可能会节省开支。已发现当地服务存在重要缺陷,特别是在二级和初级保健之间的沟通方面。这项研究进一步促使我们所在机构为骨折联络护士争取资金;我们建议其他机构效仿并聘用类似的专职人员,以确保对预防进一步骨折进行评估和治疗。

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