舌部孤立性先天性颗粒细胞瘤

Solitary congenital granular cell lesion of the tongue.

作者信息

Senoo Hitomi, Iida Seiji, Kishino Mitsunobu, Namba Noriyuki, Aikawa Tomonao, Kogo Mikihiko

机构信息

First Department of Oral and Maxillofacial Surgery, Osaka University Graduate School of Dentistry, Osaka, Japan.

出版信息

Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Jul;104(1):e45-8. doi: 10.1016/j.tripleo.2007.01.038.

DOI:10.1016/j.tripleo.2007.01.038

PMID:17577543

Abstract

Congenital granular cell lesion (CGCL) is well known to appear as the congenital epulis, predominantly on the median maxillary alveolar ridge. This lesion rarely occurs on the tongue, and only 7 cases, including 4 cases with simultaneous occurrence on the alveolar ridge, have been reported in the English literature. In this report, we report a case of congenital granular cell lesion seen on the tongue. The patient was a 7-day-old Japanese girl who presented with a polypoid mass on the anterior ventral surface near the tip of the tongue. The lesion was excised at 4 months, and its histological examination revealed large granular cells. Immunochemical staining by S-100 was negative, and it was diagnosed as congenital granular cell lesion.

摘要

先天性颗粒细胞病变（CGCL）以先天性龈瘤形式出现，主要位于上颌中切牙牙槽嵴，这是广为人知的。该病变很少发生于舌部，英文文献中仅报道过7例，其中4例同时发生于牙槽嵴。在本报告中，我们报告1例发生于舌部的先天性颗粒细胞病变。患者为一名7日龄日本女孩，舌前部腹侧近舌尖处有一息肉样肿物。病变于4个月时切除，组织学检查显示有大的颗粒细胞。S-100免疫化学染色为阴性，诊断为先天性颗粒细胞病变。