Myers Lawrence C, Compton Duane A
Department of Biochemistry and Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, New Hampshire 03755, USA.
Curr Biol. 2007 Jun 19;17(12):R460-2. doi: 10.1016/j.cub.2007.04.019.
When a eukaryotic cell divides, tension builds at centromeres as spindle forces pull chromosomes toward opposite poles during metaphase. New data show that centromeric chromatin stretches in response to these forces, revealing a mechanical role for chromatin packaging in mitosis.
当真核细胞分裂时，在中期，随着纺锤体力量将染色体拉向相反两极，着丝粒处会产生张力。新数据表明，着丝粒染色质会响应这些力量而伸展，揭示了染色质包装在有丝分裂中的机械作用。
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