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选择性经导管动脉栓塞术用于治疗肝细胞腺瘤的出血并发症或缩小肿瘤体积。

Selective transcatheter arterial embolization for treatment of bleeding complications or reduction of tumor mass of hepatocellular adenomas.

作者信息

Erdogan Deha, van Delden Otto M, Busch Olivier R C, Gouma Dirk J, van Gulik Thomas M

机构信息

Department of Surgery, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 Amsterdam, AZ, The Netherlands.

出版信息

Cardiovasc Intervent Radiol. 2007 Nov-Dec;30(6):1252-8. doi: 10.1007/s00270-007-9108-4.

Abstract

Hepatocellular adenomas (HCAs) are benign liver lesions which may be complicated by spontaneous intratumoral bleeding, with or without rupture into the abdominal cavity, or malignant degeneration. Recent advances in radiological interventional techniques now offer selective transcatheter arterial embolization (TAE) as an alternative approach to surgery as the initial treatment to stop the bleeding or as an elective treatment to reduce the tumor mass of the HCA. Herein, we report our initial experience using TAE in the management of HCA. Five female patients and one male patient presented with spontaneous hemorrhage of HCA. Four patients were initially treated with selective TAE to stop the bleeding. In two patients in whom the bleeding stopped spontaneously, TAE was electively undertaken 1 year after presentation to reduce the tumor mass of HCAs >5 cm. Selective TAE as initial treatment in patients with spontaneous bleeding of HCA with or without rupture is effective and will change the need for urgent laparotomy to control bleeding. Selective TAE may also be used as an elective treatment to reduce the tumor mass of larger HCAs.

摘要

肝细胞腺瘤(HCAs)是良性肝脏病变,可能并发自发性瘤内出血,伴或不伴有破入腹腔,或发生恶变。放射介入技术的最新进展现在提供了选择性经导管动脉栓塞术(TAE),作为手术的替代方法,作为初始治疗来止血,或作为选择性治疗来缩小HCA的肿瘤体积。在此,我们报告我们使用TAE治疗HCA的初步经验。五名女性患者和一名男性患者出现HCA自发性出血。四名患者最初接受选择性TAE治疗以止血。在两名出血自行停止的患者中,在出现症状1年后选择性进行TAE以缩小直径>5 cm的HCA的肿瘤体积。对于有或无破裂的HCA自发性出血患者,选择性TAE作为初始治疗是有效的,并且将改变为控制出血而进行紧急剖腹手术的必要性。选择性TAE也可作为选择性治疗来缩小较大HCA的肿瘤体积。

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