新种萜类诺卡氏菌，从日本诺卡氏菌病患者中分离得到。
Nocardia terpenica sp. nov., isolated from Japanese patients with nocardiosis.
作者信息
Hoshino Yasutaka, Watanabe Kayo, Iida Soji, Suzuki Shin-Ichi, Kudo Takuji, Kogure Takahisa, Yazawa Katsukiyo, Ishikawa Jun, Kroppenstedt Reiner M, Mikami Yuzuru
机构信息
National Institute of Infectious Diseases, Shinjuku, Tokyo 162-8640, Japan.
Research Center for Pathogenic Fungi and Microbial Toxicoses, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8673, Japan.
出版信息
Int J Syst Evol Microbiol. 2007 Jul;57(Pt 7):1456-1460. doi: 10.1099/ijs.0.64695-0.
Two bacterial strains isolated from different hospitals in Japan were subjected to a polyphasic analysis. Strains IFM 0406 and IFM 0706(T), producers of novel terpenoid antibiotics, were found to have morphological, biochemical, physiological and chemotaxonomic properties consistent with their classification in the genus Nocardia, except for the presence of MK-8(H(4)) as one of the predominant menaquinones in addition to the major menaquinone MK-8(H(4 omega-cyc)). The 16S rRNA gene sequence similarity of strains IFM 0406 and IFM 0706(T) was 99.9 %, and the closest members of Nocardia to these strains were the type strains of Nocardia nova and Nocardia mexicana, showing similarity of 97.5 and 97.1 %, respectively. Based on their characteristic phenotypic and phylogenetic properties, a novel species of the genus Nocardia, Nocardia terpenica sp. nov. is proposed for the two strains. The type strain is IFM 0706(T) (=JCM 13033(T)=DSM 44935(T)=NBRC 100888(T)).
对从日本不同医院分离出的两株细菌进行了多相分析。发现新型萜类抗生素的产生菌IFM 0406和IFM 0706(T)菌株，除了主要甲基萘醌MK-8(H(4ω-cyc))外还存在MK-8(H(4))作为主要甲基萘醌之一外，其形态、生化、生理和化学分类学特性与诺卡氏菌属的分类一致。IFM 0406和IFM 0706(T)菌株的16S rRNA基因序列相似性为99.9%，与这些菌株亲缘关系最近的诺卡氏菌属成员是新星诺卡氏菌和墨西哥诺卡氏菌的模式菌株，相似性分别为97.5%和97.1%。基于它们独特的表型和系统发育特性，为这两株菌提出了诺卡氏菌属的一个新种，萜类诺卡氏菌（Nocardia terpenica sp. nov.）。模式菌株为IFM 0706(T)（=JCM 13033(T)=DSM 44935(T)=NBRC 100888(T)）。
Zotero 插件