胸腺素β4与血管生成：作用模式及治疗潜力
Thymosin beta4 and angiogenesis: modes of action and therapeutic potential.
作者信息
Smart Nicola, Rossdeutsch Alex, Riley Paul R
机构信息
Molecular Medicine Unit, UCL-Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.
出版信息
Angiogenesis. 2007;10(4):229-41. doi: 10.1007/s10456-007-9077-x. Epub 2007 Jul 14.
PMID:17632766
Abstract
Here we review the mechanisms by which Thymosin beta4 (Tbeta4) regulates angiogenesis, its role in processes, such as wound healing and tumour progression and we discuss in more detail the role of Tbeta4 in the cardiovascular system and significant recent findings implicating Tbeta4 as a potential therapeutic agent for ischaemic heart disease.
摘要
在此，我们综述胸腺素β4（Tβ4）调节血管生成的机制、其在伤口愈合和肿瘤进展等过程中的作用，并更详细地讨论Tβ4在心血管系统中的作用以及近期的重要发现，这些发现表明Tβ4可能是缺血性心脏病的一种潜在治疗药物。
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