内生真菌地霉属AL4产生的杀线虫代谢产物。

Nematicidal metabolites produced by the endophytic fungus Geotrichum sp. AL4.

作者信息

Li Guo-Hong, Yu Ze-Fen, Li Xuan, Wang Xing-Biao, Zheng Li-Jun, Zhang Ke-Qin

机构信息

Key Laboratory for Conservation and Utilization of Bio-Resource, Yunnan University, Kunming 650091, PR China.

出版信息

Chem Biodivers. 2007 Jul;4(7):1520-4. doi: 10.1002/cbdv.200790131.

DOI:10.1002/cbdv.200790131

PMID:17638333

Abstract

From the endophytic fungal strain Geotrichum sp. AL4, cultivated from the leaves of the neem tree (Azadirachta indica), four compounds, 1-4, were isolated from the AcOEt extract, including two new, chlorinated, epimeric 1,3-oxazinane derivatives. All compounds were assessed for their nematicidal activities against the nematodes Bursaphelenchus xylophilus and Panagrellus redivivus, and three out of the four isolates showed noticeable bioactivities.

摘要

从印楝树（Azadirachta indica）叶片中培养出的内生真菌菌株Geotrichum sp. AL4的乙酸乙酯提取物中分离出四种化合物1-4，其中包括两种新的氯化差向异构1,3-恶嗪烷衍生物。对所有化合物针对松材线虫（Bursaphelenchus xylophilus）和复生滑刃线虫（Panagrellus redivivus）的杀线虫活性进行了评估，四种分离物中有三种表现出显著的生物活性。