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尝试脑室造影后帕金森震颤的长期消除

Long-term abolition of parkinsonian tremor following attempted ventriculography.

作者信息

Marks P V, Wild A M, Gleave J R

机构信息

Department of Neurosurgery, Auckland Hospital, New Zealand.

出版信息

Br J Neurosurg. 1991;5(5):505-8. doi: 10.3109/02688699108998480.

Abstract

Three patients are described who were selected for stereotactic thalamotomy to alleviate the tremor and rigidity of Parkinson's disease but in whom these symptoms were abolished whilst attempting ventriculography. Discrete deep brain lesions were seen on post-operative CT scan and the basis for their relieving the patients' symptoms is discussed. Although the tremor and rigidity was abolished in these cases and a favourable result ensued, ventriculography is an invasive and potentially dangerous procedure and it is therefore recommended that CT-derived thalamic targets should be employed for functional stereotaxy.

摘要

本文描述了三名患者,他们因帕金森病的震颤和僵硬症状而被选择进行立体定向丘脑切开术,但在尝试脑室造影时这些症状却消失了。术后CT扫描显示有离散的脑深部病变,并对其缓解患者症状的机制进行了讨论。尽管这些病例中的震颤和僵硬症状消失且取得了良好效果,但脑室造影是一种侵入性且有潜在危险的操作,因此建议在功能性立体定向手术中采用CT引导下的丘脑靶点。

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