阿托西班和利托君在外部胎位倒转术中的应用。
The use of atosiban and ritodrine in external cephalic version.
作者信息
Stergiotou Iosifina, Talbot Fleur, Yoong Wai
机构信息
Department of Obstetrics and Gynaecology, North Middlesex University Hospital, London, UK.
出版信息
Acta Obstet Gynecol Scand. 2007;86(8):927-9. doi: 10.1080/00016340701343123.
OBJECTIVE
To compare the efficacy of atosiban and ritodrine as tocolytic agents for successful external cephalic version (ECV). Factors affecting the success of ECV, as well as maternal and perinatal outcomes are reviewed.
METHOD
A retrospective review of women who underwent ECV with either atosiban (2004) or ritodrine (2002).
RESULTS
Atosiban and ritodrine were similarly effective (28 versus 41%, p>0.05). Side effects were more common with ritodrine. No significant adverse maternal and perinatal outcomes were recorded following procedures with either tocolytic.
CONCLUSION
Atosiban is a safe choice for ECV with less maternal side effects. However, it is no more effective than ritodrine and the benefit of safety has to be balanced against that of cost.
目的
比较阿托西班和利托君作为宫缩抑制剂用于成功实施外倒转术（ECV）的疗效。回顾影响ECV成功的因素以及母婴结局。
方法
对接受过阿托西班（2004年）或利托君（2002年）进行ECV的女性进行回顾性研究。
结果
阿托西班和利托君效果相似（分别为28%和41%，p>0.05）。利托君的副作用更常见。两种宫缩抑制剂使用后均未记录到显著的不良母婴结局。
结论
阿托西班是用于ECV的安全选择，对母体副作用较少。然而，其效果并不优于利托君，安全性的益处必须与成本相权衡。
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