Birmingham Trevor B, Hunt Michael A, Jones Ian C, Jenkyn Thomas R, Giffin J Robert
Wolf Orthopaedic Biomechanics Laboratory, Fowler Kennedy Sport Medicine Clinic, University of Western Ontario, London, Ontario, Canada.
Arthritis Rheum. 2007 Aug 15;57(6):1012-7. doi: 10.1002/art.22899.
To estimate the test-retest reliability of the peak external knee adduction moment during walking in patients with medial compartment knee osteoarthritis (OA), and to describe the interpretation of the reported values.
A total of 31 patients diagnosed with knee OA confined primarily to the medial compartment underwent quantitative gait analyses during 2 separate test sessions at least 24 hours apart and within 1 week. The peak knee adduction moment was calculated for each patient at each session based on the mean of 5 walking trials. Reliability was estimated using the intraclass correlation coefficient (ICC(2,1)) and the standard error of measurement (SEM).
The mean difference in peak adduction moments between test sessions was 0.1% body weight x height (BW x ht; 95% confidence interval [95% CI] -0.1, 0.3). The point estimate for the ICC was 0.86 (95% CI 0.73, 0.96). The point estimate for the SEM was 0.36% BW x ht (95% CI 0.29, 0.48).
The ICC suggests that the peak knee adduction moment is appropriate for use when distinguishing among patients, for example, in studies of various interventions intended to decrease dynamic load on the knee medial compartment. The SEM illustrates the importance of considering measurement error and incorporating confidence levels when interpreting an individual patient's peak knee adduction moment value.
评估内侧间室膝关节骨关节炎（OA）患者行走时膝关节最大外展力矩的重测信度，并描述所报告数值的解读方法。
共有31例主要局限于内侧间室的膝关节OA患者，在至少间隔24小时且在1周内的2次独立测试期间接受了定量步态分析。基于5次步行试验的平均值，为每位患者在每次测试中计算膝关节最大外展力矩。使用组内相关系数（ICC(2,1)）和测量标准误差（SEM）评估信度。
测试期间最大外展力矩的平均差异为0.1%体重×身高（BW×ht；95%置信区间[95%CI] -0.1，0.3）。ICC的点估计值为0.86（95%CI 0.73，0.96）。SEM的点估计值为0.36%BW×ht（95%CI 0.29，0.48）。
ICC表明，膝关节最大外展力矩适用于区分患者，例如，在各种旨在降低膝关节内侧间室动态负荷的干预研究中。SEM说明了在解释个体患者的膝关节最大外展力矩值时考虑测量误差并纳入置信水平的重要性。
