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南非强奸幸存者的特征、治疗及抗逆转录病毒预防依从性

Characteristics, treatment, and antiretroviral prophylaxis adherence of South African rape survivors.

作者信息

Carries Stanley, Muller Fritse, Muller Frederick J, Morroni Chelsea, Wilson Douglas

机构信息

Research Unit, Department of Medicine, Pietermaritzburg Hospitals Complex, Pietermaritzburg, South Africa.

出版信息

J Acquir Immune Defic Syndr. 2007 Sep 1;46(1):68-71. doi: 10.1097/QAI.0b013e31813e62f8.

Abstract

OBJECTIVE

To assess the characteristics, treatment received, and adherence to antiretroviral prophylaxis among South African rape survivors.

DESIGN

Record review of clients presenting to the Northdale Lifeline Rape Crisis Center between May 2003, and July 2004.

OUTCOME MEASURES

Data on demographics, record of treatment received with antiretroviral prophylaxis, syndromic treatment for sexually transmitted infections, and emergency contraception were collected. Adherence to antiretroviral prophylaxis was defined by filling 4 weekly prescriptions for zidovudine and lamivudine. Results of follow-up HIV testing were recorded.

RESULTS

A total of 390 records were reviewed. Ninety-five percent of clients accepted HIV testing at presentation, and HIV seroprevalence at presentation was 35.6%. Of the 233 clients testing HIV-negative, 198 (85%) received antiretroviral prophylaxis, 57% of whom were assessed as adherent. Only 55 clients (27.1%) returned for HIV testing at 6 weeks; 1 woman seroconverted.

CONCLUSIONS

Postrape care is an important service provided to South African women, and strategies should be developed to improve adherence to antiretroviral prophylaxis and follow-up testing.

摘要

目的

评估南非强奸案幸存者的特征、接受的治疗以及对抗逆转录病毒预防治疗的依从性。

设计

对2003年5月至2004年7月期间前往北戴尔生命线强奸危机中心的客户记录进行回顾。

观察指标

收集人口统计学数据、抗逆转录病毒预防治疗记录、性传播感染的症状治疗记录以及紧急避孕记录。对抗逆转录病毒预防治疗的依从性定义为填写齐多夫定和拉米夫定的四周处方。记录随访HIV检测结果。

结果

共审查了390份记录。95%的客户在就诊时接受了HIV检测,就诊时的HIV血清阳性率为35.6%。在233名HIV检测阴性的客户中,198名(85%)接受了抗逆转录病毒预防治疗,其中57%被评估为依从。只有55名客户(27.1%)在6周时返回进行HIV检测;1名女性血清转化。

结论

强奸后护理是为南非妇女提供的一项重要服务,应制定策略以提高对抗逆转录病毒预防治疗的依从性和随访检测。

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