Lamarche Yoan, Demers Philippe, Poirier Nancy C, Robitaille Danielle, Cartier Raymond
Department of Surgery, Montreal Heart Institute and Université de Montréal, Montreal, QC, Canada.
Can J Cardiol. 2007 Aug;23(10):809-13. doi: 10.1016/s0828-282x(07)70832-2.
Postoperative massive hemorrhage is a difficult clinical situation after cardiac surgery. Recombinant activated factor VII (rf-VIIa) can be a useful adjunct to surgical hemostasis and blood product transfusion. Four cases of massive hemorrhage treated with rf-VIIa after complex cardiac surgery are reported. A review of the literature and possible guidelines for the use of rf-VIIa in cardiac surgery are provided.
术后大出血是心脏手术后的一种棘手临床情况。重组活化因子VII(rf-VIIa)可作为手术止血和输血的有益辅助手段。本文报告了4例在复杂心脏手术后使用rf-VIIa治疗大出血的病例。并提供了文献综述以及在心脏手术中使用rf-VIIa的可能指导原则。