Mohindra Sandeep, Mukherjee Kanchan Kumar, Gupta Rahul, Chhabra Rajesh
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Surg Neurol. 2008 May;69(5):474-7. doi: 10.1016/j.surneu.2007.02.031. Epub 2007 Aug 17.
In spite of the decline in mortality among trauma patients, with advanced trauma care, the outcome for elderly patients remains poor. Both operative and nonoperative outcome for elderly patients after head trauma has resisted improvement.
Forty-five consecutive patients 70 years or older were included in the study. All these patients were admitted from January 2000 to June 2005. Road-traffic accidents caused most of the head injuries.
Most of the patients (n = 33) belonged to severe head injury category. Contusions were the commonest CT scan finding (n = 27), for which surgery was indicated. Unexplained clinical deterioration, in spite of timely surgery and satisfactory postoperative CT scans, in a significant number of patients (n = 29) was noteworthy. Over the same period, the comparative group of younger patients (20-40 years, n = 1026) was also analyzed.
Elderly patients experienced higher mortality and poorer functional outcome. The natural history of traumatized brain among elderly patients remains unchanged till the present times. The nihilistic scenario asks for reevaluation of interventions, relook into the neurobiology of aging brain, and aggressive research for remedial measures for such patients, especially among severe head injury group.
尽管随着先进创伤护理技术的应用,创伤患者的死亡率有所下降,但老年患者的预后仍然较差。老年患者头部创伤后的手术和非手术治疗效果均未得到改善。
本研究纳入了45例70岁及以上的连续患者。所有这些患者均于2000年1月至2005年6月入院。大多数头部损伤由道路交通事故引起。
大多数患者(n = 33)属于重度头部损伤类别。挫伤是CT扫描最常见的发现(n = 27),针对此类情况需进行手术。值得注意的是,尽管进行了及时手术且术后CT扫描结果令人满意,但仍有相当数量的患者(n = 29)出现了不明原因的临床恶化。同期,还对年轻患者的对照组(20 - 40岁,n = 1026)进行了分析。
老年患者死亡率更高,功能预后更差。迄今为止,老年患者创伤性脑损伤的自然病程并未改变。这种悲观的情况要求重新评估干预措施,重新审视衰老大脑的神经生物学,并积极研究针对此类患者的补救措施,尤其是重度头部损伤组。