犬胸腰椎椎间盘突出症的透视引导下椎间盘内氧-臭氧注射治疗
Fluoroscopic-guided intradiscal oxygen-ozone injection therapy for thoracolumbar intervertebral disc herniations in dogs.
作者信息
Han Hyun-Jung, Kim Joon-Young, Jang Ha-Young, Lee Bora, Yoon Jung-Hee, Jang Sang-Keun, Choi Seok Hwa, Jeong Soon-Wuk
机构信息
Department of Veterinary Surgery, College of Veterinary Medicine, Chungbuk National University, Chungbuk, 361-763, Republic of Korea.
出版信息
In Vivo. 2007 Jul-Aug;21(4):609-13.
BACKGROUND
To investigate the effect of oxygen-ozone (O2-O3) injection on thoracolumbar intervertebral disc herniation (IVDH) in dogs.
MATERIALS AND METHODS
Ten herniated discs of five dogs were treated with percutaneous injection of an O2-O3 gas mixture with O3 concentration of 32 microg/microl intradiscally (1.5-2 microl) under fluoroscopy guidance.
RESULTS
Five weeks after treatment, the mean size of herniated discs was measured by computed tomography and showed significant reduction of disc volumes in all animals (8.8%+/-3.82%). The degree of shrinkage was negatively linearly correlated with disc mineralization (correlation coefficient=-0.636) and statistically significant at p<0.05. All five dogs regained their gait function and none recurred.
CONCLUSION
We conclude that intradiscal O2-O3 injection can decompress affected discs by disc shrinkage.
背景
研究氧气-臭氧（O2-O3）注射对犬胸腰椎椎间盘突出症（IVDH）的影响。
材料与方法
在透视引导下，对5只犬的10个突出椎间盘经皮注射臭氧浓度为32微克/微升的O2-O3混合气体（1.5-2微升）至椎间盘内。
结果
治疗5周后，通过计算机断层扫描测量突出椎间盘的平均大小，结果显示所有动物的椎间盘体积均显著减小（8.8%±3.82%）。椎间盘缩小程度与椎间盘矿化呈负线性相关（相关系数=-0.636），且在p<0.05时具有统计学意义。所有5只犬均恢复了步态功能，且无复发。
结论
我们得出结论，椎间盘内注射O2-O3可通过椎间盘缩小使受影响的椎间盘减压。
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